Indometacin CAS: 53-86-1 Wopanga Wopanga

Indomethacin ndi nonsteroidal odana ndi kutupa wothandizila ntchito mu ululu ndi zolimbitsa kutupa kwambiri pa rheumatic matenda ndi matenda ena minofu ndi mafupa.Ndi COX (cyclooxygenase) inhibitor motero imasokoneza kupanga kwa prostaglandins.
Mitundu yatsopano ya silicon, kutengera kapangidwe ka indomethacin, apangidwa ndipo akufufuzidwa ngati mankhwala oletsa khansa.Gulu la carboxyl la indomethacin lidachitidwa ndi ma silane angapo opangidwa ndi amino-functionalized.Silane-functionalized indomethacin zotumphukira adawonetsa kuchulukitsa ka 15 kuchulukitsa kwa antiproliferative atayesedwa motsutsana ndi khansa ya kapamba.