α-Galactosidase CAS:9025-35-8

α-galactosidase(α-galactosidase, α-gal, EC 3.2.1.22) ndi exoglycosidase yomwe imayambitsa hydrolysis ya ma α-galactosidic bonds. Chifukwa imatha kuwola melibiose, imatchedwanso melibiase, yomwe imayambitsa hydrolysis ya ma α-galactosidic bonds. Izi zimapangitsa kuti zikhale zothandiza pakukonza ndikuchotsa zinthu zotsutsana ndi zakudya muzakudya ndi zakudya zopangidwa ndi soya. Kuphatikiza apo, imatha kusintha mtundu wa magazi a B→O m'munda wazachipatala, kukonza magazi onse, ndikuchita gawo lofunikira pa chithandizo chobwezeretsa ma enzyme a matenda a Fabry. α-galactosidase imathanso kugwira ntchito pa ma polysaccharides ovuta, ma glycoproteins ndi ma glycosphingoses okhala ndi ma α-galactosidic bonds. Ma α-galactosidases ena amathanso transgalactosylate pamene kuchuluka kwa substrate kuli kolemera kwambiri, ndipo izi zitha kugwiritsidwa ntchito popanga oligosaccharides ndikukonzekera ma derivatives a cyclodextrin. Kukula kwa neutrophil kapena pH-stable α-galactosidase komanso kufunafuna tizilombo toyambitsa matenda kapena zomera zomwe zimapanga ma enzyme ambiri kwakhala malo ofufuzira kwambiri m'zaka zaposachedwa. Ma α-galactosidases ambiri osatentha nawonso pang'onopang'ono akopa chidwi cha asayansi chifukwa cha luso lawo, akuyembekeza kugwiritsa ntchito kukhazikika kwawo kutentha kuti agwiritse ntchito bwino kwambiri m'mafakitale, ndikuwonetsa mitundu yosiyanasiyana ya ntchito m'magawo aukadaulo, ukadaulo ndi zamankhwala.