2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ndi mankhwala omwe amagwiritsidwa ntchito kwambiri mu carbohydrate chemistry ndi glycosylation reactions.Ndiwochokera ku α-D-galactopyranose, mtundu wa shuga, pomwe magulu a hydroxyl pa 2, 3, 4, ndi 6 malo a mphete ya galactopyranose ndi acetylated.Kuonjezera apo, anomeric carbon (C1) ya shuga imatetezedwa ndi gulu la trichloroacetimidate, lomwe limapanga electrophile yamphamvu panthawi ya glycosylation reaction.

Pawiri nthawi zambiri amagwiritsidwa ntchito ngati glycosylating wothandizila kuyambitsa galactose moieties mu mamolekyu osiyanasiyana, monga mapuloteni, peptides, kapena mamolekyu ang'onoang'ono organic.Izi zitha kutheka pochita pawiri ndi nucleophile (mwachitsanzo, magulu a hydroxyl pa molekyulu yomwe mukufuna) pamikhalidwe yoyenera.Gulu la trichloroacetimidate limathandizira kulumikizidwa kwa gawo la galactose ku molekyulu yomwe mukufuna, zomwe zimapangitsa kuti pakhale mgwirizano wa glycosidic.

Pagululi nthawi zambiri amagwiritsidwa ntchito popanga glycoconjugates, glycopeptides, ndi glycolipids.Imapereka njira yosunthika komanso yothandiza yosinthira mamolekyu okhala ndi zotsalira za galactose, zomwe zitha kukhala zofunikira m'magawo osiyanasiyana, kuphatikiza maphunziro achilengedwe, njira zoperekera mankhwala, kapena chitukuko cha katemera.

Konzani kapena Funsani Mtengo

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Kugwiritsa Ntchito ndi Zotsatira

Glycosylation: Pawiriyi imakhudzidwa ndi mamolekyu osiyanasiyana olandila okhala ndi magulu a hydroxyl, monga ma alcohols kapena ma amines, kupanga ma glycosidic bond.Izi zimathandiza kuti galactose ilowe mu molekyulu yovomerezeka, zomwe zimapangitsa kuti glycoconjugates, glycopeptides, kapena glycolipids apangidwe.

Maphunziro a biochemical ndi biological: Pawiriyi imathandiza ofufuza kuti aphunzire ntchito zachilengedwe komanso kuyanjana kwa mamolekyu okhala ndi galactose.Mwa kusankha kuphatikizira galactose ku mapuloteni, ma peptides, kapena ma biomolecules ena, ofufuza amatha kufufuza momwe amagwirira ntchito pama cell, kuyanjana kwa receptor-ligand, ndi njira zamatenda.

Njira zoperekera mankhwala: Pawiriyi ingagwiritsidwe ntchito kusintha mamolekyu a mankhwala okhala ndi zotsalira za galactose, kuthandizira kuperekedwa kwa mankhwala kumatenda kapena ma cell.Galactose imatha kukhala ngati ligand yolunjika, kuzindikira zolandilira zomwe zimawonetsedwa pamwamba pa maselo, makamaka hepatocytes.Pophatikizira galactose ku mankhwala, ofufuza amatha kupititsa patsogolo kusankha kwawo komanso kuchita bwino pamankhwala omwe akuwongolera.

Kukula kwa katemera: Mamolekyu okhala ndi galactose amagwira ntchito yofunika kwambiri pakuyankha kwa chitetezo chamthupi, chifukwa amazindikiridwa ndi ma lectin omwe amapezeka pama cell a chitetezo chamthupi.Pophatikiza ma antigen ndi magulu a galactose pogwiritsa ntchito mankhwalawa, ofufuza amatha kulimbitsa chitetezo chamthupi ndikupanga katemera wogwira mtima.

Kaphatikizidwe ka Chemical: Pawiriyi itha kugwiritsidwa ntchito m'mapangidwe osiyanasiyana amankhwala komwe kusinthidwa kwa galactose kumafunika.Izi zikuphatikizapo kukonzekera zovuta zama carbohydrate, oligosaccharides, kapena glycomimetics, zomwe zingagwiritsidwe ntchito mopitilira muyeso wamankhwala kapena ngati zida zofufuzira.

Product Chitsanzo

Kulongedza katundu:

Zina Zowonjezera:

Kupanga	C16H20Cl3NO10
Kuyesa	99%
Maonekedwe	White ufa
CAS No.	86520-63-0
Kulongedza	Zing'onozing'ono ndi zambiri
Shelf Life	zaka 2
Kusungirako	Sungani pamalo ozizira ndi owuma
Chitsimikizo	ISO.