4-Bromo-1-methyl-1H-pyrazole-3-carbonitrile CAS:287922-71-8

4-Bromo-1-methyl-1H-pyrazole-3-carbonitrile imagwira ntchito yofunika kwambiri ngati pakati pa kupanga mankhwala ovuta, opatsa thanzi omwe ali ndi ntchito zomwe zingatheke pa mankhwala. Kuphatikizidwa kwake mu mamolekyulu kumathandiza ofufuza kufufuza mankhwala atsopano omwe akuyang'ana madera osiyanasiyana ochiritsira monga mankhwala ophera bowa, mankhwala ophera udzu, kapena mankhwala a agrochemicals. Kupezeka kwa pyrazole core ndi gulu la cyano kumayambitsa reactivity yeniyeni ndi katundu wa pharmacophoric, zomwe zimapangitsa kuti ikhale yofunikira pa kafukufuku wa chemistry yamankhwala. Mu zoyesayesa zopeza mankhwala, mankhwalawa angagwiritsidwe ntchito ngati poyambira popanga mankhwala omwe angakhalepo, pogwiritsa ntchito mawonekedwe ake kuti asinthe ntchito ya zamoyo ndi katundu wa pharmacokinetic. Kuphatikiza apo, reactivity yapadera ya gulu la cyano imapereka mwayi wowonjezera kutulutsa, zomwe zingayambitse chitukuko cha mamolekyu atsopano okhala ndi katundu wowonjezera wa zamoyo. Kuphatikiza apo, m'malo ophunzirira ndi mafakitale, ofufuza angagwiritse ntchito nyumbayi kukonzekera malaibulale a zinthu zosiyanasiyana zochokera ku kafukufuku wa kapangidwe ka ntchito, kuthandizira kuzindikira mankhwala a lead omwe ali ndi zotsatira zomwe zimafunidwa pazamoyo. Udindo wake pakupanga mankhwala umafikira pakupanga mankhwala ophatikizana ndi kupanga njira zatsopano zopangira, kuwonetsa kufunika kwake kwakukulu m'magawo asayansi. Ponseponse, 4-Bromo-1-methyl-1H-pyrazole-3-carbonitrile imagwira ntchito yofunika kwambiri pakufunafuna njira zatsopano zopezera mankhwala ndi kafukufuku wa mankhwala, zomwe zimapereka nsanja yopangira mamolekyu osiyanasiyana ogwira ntchito m'thupi komanso mankhwala ophatikizika.