beta-Nicotinamide adenine dinucleotide trihydrate CAS:53-84-9

Kupanga mphamvu: β-NAD+ ndi gawo lofunika kwambiri pakusintha chakudya kukhala mphamvu. Imagwira ntchito ngati coenzyme mu kupuma kwa maselo, zomwe zimathandiza kusamutsa ma elekitironi kuchokera ku metabolites kupita ku unyolo wonyamula ma elekitironi. Kusamutsa ma elekitironi kumeneku ndikofunikira kwambiri pakupanga ATP, yomwe ndi ndalama yayikulu yamphamvu ya maselo.

Kukonza DNA: β-NAD+ imagwira ntchito mu njira zokonzanso DNA. Imagwira ntchito ngati gawo la ma enzyme monga PARPs (Poly [ADP-ribose] polymerases), omwe amagwiritsa ntchito β-NAD+ kukonza DNA yowonongeka poyankha kupsinjika kwa maselo osiyanasiyana monga kuwonongeka kwa DNA komwe kumachitika chifukwa cha kuwala kwa dzuwa, poizoni, kapena kupsinjika kwa okosijeni.

Kupereka zizindikiro kwa ma cell: β-NAD+ yakhala ngati molekyulu yofunika kwambiri yopereka zizindikiro yomwe imakhudzidwa ndi njira zosiyanasiyana za ma cell. Imatha kugwira ntchito ngati choyambira cha mamolekyulu osiyanasiyana opereka zizindikiro, monga cyclic ADP-ribose ndi NAADP, zomwe zimawongolera kutulutsidwa kwa calcium ndi kuperekedwa kwa zizindikiro. Kuphatikiza apo, kagayidwe ka β-NAD+ kangakhudze momwe majini amagwirira ntchito, ukalamba, ndi njira zina za thupi zimagwirira ntchito.

Kugwiritsa ntchito mankhwala: Kuonjezera β-NAD+ ndi kusintha kwa milingo ya β-NAD+ kukufufuzidwa kuti mudziwe momwe mankhwala angagwiritsire ntchito. Kafukufuku waposachedwapa akusonyeza kuti kuwonjezera milingo ya β-NAD+ kungakhale ndi zotsatira zabwino pa matenda okhudzana ndi ukalamba, matenda a mitsempha, matenda a kagayidwe kachakudya, komanso thanzi la mtima. Palinso kafukufuku wopitilira wokhudza kugwiritsa ntchito zinthu zoyambira β-NAD+, monga nicotinamide riboside ndi nicotinamide mononucleotide, ngati zowonjezera zomwe zingathandize kuwonjezera milingo ya β-NAD+ m'thupi.