Boc-D-Lys(2-Cl-Z)-OH CAS:57096-11-4

Boc-D-Lys(2-Cl-Z)-OH imagwiritsidwa ntchito kwambiri popanga ma peptide opangidwa mwapadera okhala ndi machitidwe ndi magwiridwe antchito enaake. Monga mtundu wotetezedwa wa D-lysine, imalola kulowetsedwa kolamulidwa kwa zotsalira za D-lysine mu unyolo wa peptide womwe ukukula, kuletsa zotsatira zoyipa komanso kuthandizira kupanga ma peptide ovuta okhala ndi mawonekedwe opangidwa. Mu bioconjugation ndi chemistry biology, Boc-D-Lys(2-Cl-Z)-OH imagwira ntchito ngati chomangira chosiyanasiyana chopangira ma peptide ogwira ntchito, ma probe olembedwa, ndi mankhwala ochiritsira okhala ndi peptide. Kugwiritsa ntchito kwake kumathandiza kusintha molondola ma peptide ndi mapuloteni, kuthandizira kupanga mamolekyulu ambiri ogwira ntchito okhala ndi kukhazikika kowonjezereka, kutsimikizika kwa cholinga, kapena kuthekera kojambula zithunzi pazinthu zosiyanasiyana zamankhwala. Kuphatikiza apo, pakupezedwa kwa mankhwala ndi chitukuko cha mankhwala, Boc-D-Lys(2-Cl-Z)-OH imagwiritsidwa ntchito popanga ma conjugates a peptide ndi ma peptide osinthidwa okhala ndi mbiri yabwino ya pharmacokinetic ndi zochita zamoyo. Kusintha kumeneku kungawonjezere mphamvu, kusankha, komanso kupereka mankhwala ochokera ku peptide, zomwe zimathandiza kupititsa patsogolo mankhwala olondola komanso njira zochiritsira. Ponseponse, kudalirika kwa Boc-D-Lys(2-Cl-Z)-OH komanso kusinthasintha kwa kapangidwe ka peptide ndi bioconjugation kumapangitsa kuti ikhale chida chofunikira kwambiri popititsa patsogolo kafukufuku wokhudza kupeza mankhwala, biology ya mankhwala, ndi proteomics, zomwe zimapereka mwayi wosiyanasiyana wopanga mapulogalamu atsopano a biomedical.