Butyrylthiocholine iodide CAS:1866-16-6

Butyrylcholine iodide ndi mankhwala opangidwa omwe amagwiritsidwa ntchito kwambiri mu kafukufuku wa biochemical ndi neurobiological ngati gawo lophunzirira ntchito ya ma enzymes a cholinesterase. Ndi ofanana ndi acetylcholine koma ali ndi gulu lalikulu la acyl (butyryl) m'malo mwa gulu la acetyl.

Kugwiritsa ntchito kwakukulu kwa butyrylcholine iodide kumachitika mu enzyme assays kuti ayesere ntchito ya ma enzyme a butyrylcholinesterase (BChE). BChE ndi enzyme yomwe imayambitsa hydrolysis ya butyrylcholine. Poyesa kuchuluka kwa hydrolysis, ofufuza amatha kudziwa ntchito ya BChE, yomwe ndi yofunika kwambiri pomvetsetsa chizindikiro cha cholinergic ndi kagayidwe kachakudya.

Kuwonjezera pa kuyesa kwa enzymatic, butyrylcholine iodide ingagwiritsidwenso ntchito mu maphunziro okhudzana ndi chitukuko cha mankhwala, neuropharmacology, ndi toxicology. Ingagwiritsidwe ntchito kuwunika momwe mankhwala amakhudzira ntchito ya BChE poyesa mankhwala kapena maphunziro a poizoni.