Clozapine N-oxide CAS: 34233-69-7 Mtengo wa Wopanga

Clozapine N-oxide ndi chinthu chomwe chimapezeka mu mankhwala oletsa matenda amisala otchedwa clozapine. Kafukufuku wapeza chidwi chifukwa cha kugwiritsidwa ntchito kwake mu optogenetics, njira yomwe imagwiritsa ntchito kuwala kuwongolera maselo m'thupi lamoyo, makamaka ma neuron. Mu maphunziro a optogenetic, clozapine N-oxide ingagwiritsidwe ntchito kuwongolera ntchito ya ma receptor opanga omwe amayendetsedwa ndi mankhwala opanga okha (DREADDs), omwe ndi ma switch a molecular omwe amapangidwa omwe amayankha ku clozapine N-oxide. Kugwiritsa ntchito kumeneku kumalola ofufuza kusintha ma neural circuits enaake ndikuphunzira ntchito yawo. Kuphatikiza apo, clozapine N-oxide yaphunziridwanso chifukwa cha zotsatira zake zochiritsira matenda amisala ndi mitsempha.