Colistin Sulfate CAS:1264-72-8

Colistin sulfate imagwiritsidwa ntchito pochiza matenda akuluakulu a bakiteriya omwe amayamba chifukwa cha mabakiteriya ambiri osagwiritsa ntchito mankhwala a gram-negative. Nthawi zambiri imasungidwa pochiza matenda monga chibayo chogwirizana ndi mpweya, sepsis, matenda amkodzo, ndi matenda a m'magazi akayambitsidwa ndi tizilombo toyambitsa matenda monga Pseudomonas aeruginosa, Acinetobacter baumannii, ndi Klebsiella pneumoniae. Mlingo woyenera ndi kupereka colistin sulfate ndikofunikira kuti pakhale zotsatira zabwino kwambiri za chithandizo pomwe kuchepetsa chiopsezo cha zotsatirapo zoyipa. Chifukwa cha kuthekera kwake kukhala ndi poizoni wa nephrotoxicity ndi neurotoxicity, kuyang'anira bwino ntchito ya impso ndi momwe mitsempha ilili ndikofunikira panthawi ya chithandizo. Kusintha kwa mlingo kungafunike kutengera mawonekedwe a wodwala payekha komanso momwe impso imagwirira ntchito. Ogwira ntchito zachipatala ayenera kuchita mayeso oti munthu azitha kudwala asanayambe kulandira chithandizo ndi colistin sulfate kuti atsimikizire kuti chamoyo chomwe chikudwala chikulandira chithandizo choyenera. Zotsatira zoyipa zitha kuphatikizapo kulephera kwa impso, zovuta za kupuma, komanso kukhudzidwa kwa hypersensitivity, zomwe zimafuna kuyang'aniridwa mosamala panthawi yonse ya chithandizo. Pomaliza, colistin sulfate imagwira ntchito yofunika kwambiri polimbana ndi matenda omwe amayamba chifukwa cha mabakiteriya ambiri osagwiritsa ntchito mankhwala a gram-negative ndipo iyenera kugwiritsidwa ntchito mwanzeru kuti isunge kugwira ntchito kwake ndikuchepetsa kukula kwa kukana kwina. Kutsatira mfundo zoyendetsera maantibayotiki ndikofunikira kwambiri pakugwiritsa ntchito bwino colistin sulfate kuti zotsatira za wodwala ziwonjezeke bwino komanso kupewa kufalikira kwa mitundu yolimbana ndi mabakiteriya.