Duloxetine HCL CAS: 136434-34-9 Wopanga Wopanga

Duloxetine HCL ndi mtundu wamchere wa antidepressant mankhwala duloxetine.Idapangidwa bwino ndi Eli Lilly Company.Mphamvu yake ya pharmacological ndi yofanana ndi duloxetine.Duloxetine hydrochloride ndi mtundu watsopano wosankha wapawiri inhibitor wa 5 hydroxy trptamine (5-HT) ndi norepinephrine reuptake, ndipo motero amakhala ndi antidepressant effect, komanso kukhala ndi zotsatira zolepheretsa kupweteka kwapakati.Kapangidwe kake ka mankhwala ndikutha kuletsa kubwereza kwa neuronal pre-synaptic membrane pa 5-hydroxy trptamine ndi norepinephrine koma m'malo mwake kumakhala ndi zoletsa zochepa pakubwezeretsanso kwa dopamine.Duloxetine hydrochloride imasonyezedwa chifukwa cha kuvutika maganizo ndipo imakhala yothandiza pochiza kuvutika maganizo kwamkati komanso komwe sikungatheke komanso kumva ululu wokhudzana ndi kuvutika maganizo.Ili ndi mlingo wochizira wa 60mg/d~120mg/d wokhala ndi chitetezo chabwino komanso zokumana nazo zocheperako monga nseru, kuuma pakamwa, kudzimbidwa, kusafuna kudya, kutopa, kugona, komanso kutuluka thukuta.Chizindikiro china ndi ululu wobwera chifukwa cha matenda a diabetesic neuropathy.