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1 '1-Bis(diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, yokhala ndi formula ya mankhwala [Pd(dppf)Cl₂·CH₂Cl₂], ndi chinthu cha organometallic chokhala ndi palladium(II) chogwirizana ndi dppf ligand ndi ma chlorides mu dichloromethane solvent. Chimagwiritsidwa ntchito kwambiri popanga ndi kusakaniza kwa organic.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea ndi mankhwala omwe amadziwika ndi kukhalapo kwa gulu la thiourea lomwe limalumikizidwa ndi gulu la 6-bromopyridin-2-yl. Mankhwalawa akopa chidwi cha mankhwala chifukwa cha ntchito zake zosiyanasiyana zamankhwala komanso momwe angagwiritsire ntchito pochiza. Mapangidwe ake apadera amapereka njira zopangira mankhwala atsopano okhala ndi zolinga zenizeni zamoyo, zomwe zimapangitsa kuti ikhale chinthu chofunikira kwambiri pakupeza ndi kupanga mankhwala.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, yomwe imadziwika kuti TMDBP, ndi mankhwala omwe ali m'gulu la ma esters a phenolic boronic. Kapangidwe kake ka molekyulu kamakhala ndi gulu la phenolic hydroxyl lomwe limalumikizidwa ku mphete ya phenyl yokhala ndi boron-containing cyclic ester moiety. Mankhwalawa ndi ofunikira kwambiri mu kapangidwe ka organic, makamaka mu Suzuki-Miyaura cross-coupling reactions, komwe amagwira ntchito ngati boronic ester reagent yofunika kwambiri. Kuphatikiza apo, kapangidwe kake kokhazikika ka cyclic boronate komanso chilengedwe chake cholepheretsedwa zimapangitsa kuti ikhale yothandiza popanga ma ligands a transition metal-catalyzed reactions komanso pakupanga zinthu zogwirira ntchito.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS:761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester ndi mankhwala omwe amagawidwa ngati boronic ester. Kapangidwe kake ka molekyulu kamakhala ndi boronic acid yomwe imalumikizidwa ku mphete ya pyrazole yomwe imasinthidwa ndi gulu la pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Mankhwalawa ndi ofunikira kwambiri pakupanga zinthu zachilengedwe, makamaka mu Suzuki-Miyaura cross-coupling reactions, komwe amagwira ntchito ngati boronic ester reagent yosinthasintha. Kuphatikiza apo, kukhazikika kwake, kusankha kwake, komanso kugwirizana kwake ndi zinthu zosiyanasiyana zomwe zimachitika zimapangitsa kuti ikhale yothandiza pakupanga mankhwala, mankhwala a agrochemicals, ndi zinthu zogwira ntchito.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- ndi mankhwala osakanikirana a bicyclic okhala ndi kapangidwe ka cyclopenta[b]pyrrole core ndi unyolo wa mbali wa hexahydro-1H-pyrrole-3a(1H)-methanol. Molekyu iyi ndi yofunika kwambiri mu chemistry yamankhwala chifukwa cha ntchito zake zamankhwala. Kapangidwe kake kapadera kamapereka mwayi wopanga mankhwala atsopano, makamaka okhudzana ndi matenda amitsempha ndi matenda ena komwe kusintha kwa ma neurotransmitter receptors ndi zonyamula ndikofunikira. Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- imagwira ntchito ngati malo osungira akatswiri azamankhwala omwe amafufuza mankhwala atsopano omwe ali ndi mphamvu zabwino za pharmacokinetic komanso zotsatirapo zochepa.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid ndi molekyulu yovuta yokhala ndi mphete ya pyrrolidine yomwe imalowetsedwa m'malo mwa gulu la tert-butoxycarbonyl pamalo 1 ndi gulu la 3-(trifluoromethyl)phenyl pamalo 4. Phala ili ndi lofunika kwambiri mu mankhwala, makamaka chifukwa cha kuthekera kwake ngati mankhwala opangira mankhwala. Kapangidwe kake kovuta kamapereka mwayi wopanga mankhwala atsopano okhala ndi mphamvu zopangidwira mankhwala, makamaka kulunjika njira zomwe zimakhudzidwa ndi matenda otupa, khansa, kapena matenda apakati a mitsempha.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ndi mankhwala omwe amadziwika ndi mphete ya pyrrolidine yomwe imasinthidwa ndi gulu la ethyl pamalo a 3 ndi gulu la tert-butyl pamalo a 1. Mankhwalawa akope chidwi cha mankhwala chifukwa cha kapangidwe kake ka stereochemical komanso momwe angagwiritsire ntchito mankhwala. Makonzedwe ake apadera amapereka njira zopangira mankhwala atsopano okhala ndi zolinga zenizeni zamoyo, zomwe zimapangitsa kuti ikhale chuma chamtengo wapatali pakupeza mankhwala ndi ntchito zopanga.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ndi mankhwala omwe amasiyanitsidwa ndi mphete ya pyrrolidine yomwe imasinthidwa ndi gulu la ethyl pamalo a 3 ndi gulu la tert-butyl pamalo a 1. Mankhwalawa akopa chidwi mu mankhwala chifukwa cha zovuta zake komanso momwe amagwiritsidwira ntchito ndi mankhwala. Kapangidwe kake kapadera kamapereka mwayi wopanga mankhwala atsopano okhala ndi zolinga zenizeni zamoyo, zomwe zimapangitsa kuti ikhale chinthu chofunikira kwambiri pakupeza mankhwala ndi ntchito zopanga.
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4-Hydroxyphenylboronic acid pinacol ester CAS:269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, yomwe imadziwikanso kuti 4-HPBA pinacol ester, ndi mankhwala omwe ali m'gulu la ma ester a boronic. Kapangidwe kake ka molekyulu kamakhala ndi gawo la boronic acid lomwe limalumikizidwa ku mphete ya phenyl yomwe imasinthidwa ndi gulu la pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Mankhwalawa ndi ofunikira kwambiri pakupanga zinthu zachilengedwe, makamaka mu Suzuki-Miyaura cross-coupling reactions, komwe amagwira ntchito ngati boronic ester reagent yosinthasintha. Kuphatikiza apo, kukhazikika kwake, kusavuta kugwiritsa ntchito, komanso kugwirizana ndi zinthu zosiyanasiyana zomwe zimachitika zimapangitsa kuti ikhale yothandiza pakupanga mankhwala, zinthu zachilengedwe, ndi zinthu zothandiza.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride ndi mankhwala opangidwa ndi gulu logwira ntchito la carbamate lomwe limalumikizidwa ku mphete ya piperidine yomwe imasinthidwa ndi gulu la benzyl pa atomu ya nayitrogeni ndi gulu la propyl pa atomu ya kaboni. Mankhwalawa ayambitsa chidwi ndi mankhwala chifukwa cha zovuta zake komanso momwe angagwiritsire ntchito mankhwala. Dongosolo lake lapadera limapereka mwayi wopanga mankhwala atsopano okhala ndi zolinga zenizeni zamoyo, zomwe zimapangitsa kuti ikhale chinthu chofunikira kwambiri pakupeza mankhwala ndi ntchito zopanga.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic acid CAS:333432-28-3
9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, yomwe nthawi zambiri imatchedwa DMFBA, ndi mankhwala omwe ali m'gulu la ma boronic acid. Kapangidwe kake ka molekyulu kali ndi boronic acid yomwe imalumikizidwa ku fluorene scaffold yomwe imasinthidwa ndi magulu awiri a methyl pamalo a 9. Kapangidwe kameneka kali ndi kufunika kwakukulu mu kapangidwe ka organic, makamaka mu Suzuki-Miyaura cross-coupling reactions, komwe kamagwira ntchito ngati boronic acid reagent yosinthasintha. Kuphatikiza apo, kapangidwe kake kolimba komanso kolepheretsedwa kumapangitsa kuti ikhale yofunikira pakupanga ligand pakusintha kwa metal-catalyzed reactions komanso pakupanga zinthu zogwirira ntchito.
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4-Carboxyphenylboronic acid CAS: 14047-29-1
4-Carboxyphenylboronic acid, yomwe imadziwikanso kuti 4-Carboxyphenylboronic acid kapena 4-CPBA, ndi mankhwala omwe ali m'gulu la ma boronic acid. Amadziwika ndi gulu lake la boronic acid functional (-B(OH)₂) lolumikizidwa ku mphete ya phenyl yomwe imasinthidwa ndi gulu la carboxylic acid (-COOH) pamalo a para. Mankhwalawa amagwiritsidwa ntchito kwambiri popanga zinthu zachilengedwe, makamaka mu Suzuki-Miyaura cross-coupling reactions kuti apange ma carbon-carbon bonds. Kuphatikiza apo, kuthekera kwake kumangirira ku diols ndi shuga kwapangitsa kuti agwiritsidwe ntchito popanga masensa owunikira shuga komanso mu chemistry yamankhwala popanga ma enzyme inhibitors ndi ma receptor ligands.
