Opanga ndi Ogulitsa Mankhwala Abwino - China Fakitale Yabwino Yamankhwala

4-PHENOXYPHENYLBORONIC ACID CAS:51067-38-0

4-Phenoxyphenylboronic acid ndi boronic acid derivative yokhala ndi molecular formula ya C12H10BO2. Ili ndi mphete ziwiri za phenyl zolumikizidwa kudzera mu ether bond, ndi gulu la boronic acid lolumikizidwa ku imodzi mwa mphete za phenyl.

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Acetophenone CAS:98-86-2

Acetophenone, yomwe imadziwikanso kuti phenyl ethanone kapena 1-phenylethanone, ndi ketone yosavuta yonunkhira. Fomula yake ya molekyulu ndi C8H8O, ndipo ndi madzi opanda mtundu wokhala ndi fungo labwino komanso lokoma la maluwa. Acetophenone ndi chinthu chofunikira kwambiri popanga mankhwala ambiri ndi mankhwala.

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N-phenyloxindole CAS:3335-98-6

N-Phenyloxindole ndi mankhwala opangidwa ndi heterocyclic omwe ali m'gulu la indole, okhala ndi molekyulu ya C11H9NO. Ili ndi indole core, yomwe ndi kapangidwe ka bicyclic komwe kali ndi mphete ya benzene yolumikizidwa ku mphete ya pyrrole. Mphete ya indole ndi chinthu chodziwika bwino chomwe chimapezeka muzinthu zambiri zachilengedwe ndi mankhwala.

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Asidi wa Carbamic,[(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-, 1,1-dimethylethylester CAS:486460-23-5

Carbamic acid, [(1R)-3-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl] -1,1-dimethylethylester, ndi chinthu chovuta chachilengedwe chokhala ndi mphete zambiri za heterocyclic ndi magulu ogwira ntchito, zomwe zimapangitsa kuti chikhale chosangalatsa kwambiri pa ntchito zosiyanasiyana.

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5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine CAS:799842-07-2

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine ndi mankhwala ovuta achilengedwe omwe amagwira ntchito yofunika kwambiri ngati chinthu chopangira mankhwala mumakampani opanga mankhwala. Kapangidwe kake kamakhala ndi pyrimidine core, mphete ya zonunkhira yokhala ndi ziwalo zisanu yokhala ndi maatomu a nayitrogeni pamalo 1, 3, ndi 5, yomwe ndi kapangidwe kofala m'mankhwala ambiri ogwira ntchito m'thupi.

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4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl CAS:147118-37-4

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl ndi mankhwala ovuta okhala ndi magulu angapo ogwira ntchito.

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Rosuvastatin Intermediates ZD9 CAS:289042-10-0

Mankhwala apakati a Rosuvastatin ZD9 ndi mndandanda wa mankhwala achilengedwe omwe amagwira ntchito ngati njira yofunika kwambiri popanga rosuvastatin, mankhwala otchuka a statin omwe amagwiritsidwa ntchito pochepetsa cholesterol. Mankhwala apakati awa ndi gawo lofunika kwambiri popanga mankhwala, kutseka kusiyana pakati pa njira zoyambira zopangira ndi mankhwala omaliza.

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3-tert-Butoxycarbonylphenylboronic acid CAS:220210-56-0

3-tert-Butoxycarbonylphenylboronic acid ndi mankhwala apadera omwe amaphatikiza makhalidwe a boronic acid ndi phenol yotetezedwa. Kupezeka kwa gulu loteteza la tert-butyloxycarbonyl (BOC) pa gulu la phenolic hydroxyl kumawonjezera kukhazikika kwa mankhwalawa, pomwe magwiridwe antchito a boronic acid amatsegula mwayi wochitapo kanthu kwina.

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4-(3-fluorobenzyloxy)benzaldehyde CAS:66742-57-2

4-(3-fluorobenzyloxy)benzaldehyde ndi chinthu chochokera ku benzaldehyde chokhala ndi 3-fluorobenzyloxy substituent. Ndi aldehyde yonunkhira bwino yokhala ndi molekyulu ya C12H10FO2.

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4-Chlorophenylboronic acid CAS:1679-18-1

4-Chlorophenylboronic acid ndi chinthu chomwe chimafunika kwambiri pakupanga zinthu zachilengedwe, mankhwala, ndi sayansi ya zinthu. Chimapangidwa ndi gulu la boronic acid lomwe limalumikizidwa ku mphete ya phenyl yomwe imalowetsedwa m'malo mwa atomu ya chlorine. Kapangidwe kameneka kamapereka mankhwala apadera ku chinthucho, zomwe zimapangitsa kuti chikhale chofunikira m'njira zosiyanasiyana.

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Sitagliptin CAS:486460-32-6

Sitagliptin, yomwe imadziwika ndi dzina lodziwika bwino la Januvia, ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga amtundu wachiwiri. Ili m'gulu la mankhwala otchedwa DPP-4 inhibitors, omwe amagwira ntchito powonjezera mphamvu ya insulin. Sitagliptin idavomerezedwa ndi FDA mu 2006 ndipo kuyambira pamenepo yakhala mankhwala operekedwa kwambiri kuti azitha kuyang'anira kuchuluka kwa shuga m'magazi mwa odwala matenda a shuga amtundu wachiwiri.

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N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride CAS:482577-59-3

N-[(2'-Cyano[1,1'-Biphenyl]-4-yl)methyl]-Methyl Ester L-Valine Monohydrochloride ndi chinthu chopangidwa ndi organic chokhala ndi formula ya molekyulu ya C21H23NO3. Ndi ester derivative ya L-valine, amino acid yofunika, ndipo ili ndi gulu la cyano lolumikizidwa ku mphete ya biphenyl.

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