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ZEBULARINE CAS:3690-10-6
Zebularine ndi cytidine yomwe ili ndi kapangidwe kake kapadera ka shuga wa 2′-deoxy-2′-fluoro-D-ribose ndi uracil base yomwe yasinthidwa. Yatchuka kwambiri m'munda wa epigenetics chifukwa cha kuthekera kwake kuletsa DNA methyltransferases, ma enzyme omwe amachititsa kuwonjezera magulu a methyl ku DNA. Izi zimapangitsa zebularine kukhala mankhwala ochiritsira matenda osiyanasiyana okhudzana ndi methylation ya DNA yosazolowereka, kuphatikizapo khansa.
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5,7-Dichloro-1H-indole-2,3-dione CAS:6374-92-1
5,7-Dichloro-1H-indole-2,3-dione ndi chinthu chochokera ku indole-2,3-dione chomwe chili ndi chlorine, chomwe chili ndi zinthu ziwiri zolowa m'malo mwa chlorine pamalo a 5 ndi 7 a mphete ya indole. Chomerachi chimadziwika ndi kapangidwe kake kapadera, kuphatikiza magulu onse awiri a carbonyl omwe amathandizira kuti chigwire ntchito. Kapangidwe kake kapadera ka mankhwala kamamupangitsa kukhala wofunika kwambiri pakupanga zinthu zachilengedwe komanso mankhwala.
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4-Methylbenzyl alcohol CAS:589-18-4
Mowa wa 4-Methylbenzyl, womwe umadziwikanso kuti p-tolylmethanol, ndi mowa wonunkhira bwino wokhala ndi gulu la methyl lomwe limalumikizidwa ku mphete ya benzene pamalo a para poyerekeza ndi gulu la hydroxymethyl. Chosakaniza ichi ndi madzi opanda mtundu, okhuthala okhala ndi fungo labwino, ndipo amasungunuka mu zosungunulira zachilengedwe. Chifukwa cha kapangidwe kake, mowa wa 4-methylbenzyl umagwira ntchito yofunika kwambiri popanga zinthu zachilengedwe ndipo umagwiritsidwa ntchito m'mafakitale osiyanasiyana.
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Mithramycin A CAS:778-94-9
2-Nitro-4- (trifluoromethyl)benzonitrile ndi mankhwala omwe amadziwika ndi magulu ake ogwira ntchito a nitro ndi trifluoromethyl omangiriridwa ku mphete ya benzene. Ili ndi gulu la nitrile (-CN), lomwe limawonjezera reactivity yake m'njira zosiyanasiyana zopangira zinthu zachilengedwe. Kupezeka kwa trifluoromethyl kumawonjezera lipophilicity ndi kukhazikika kwa molekyulu, zomwe zimapangitsa kuti ikhale yofunika kwambiri mu chemistry yamankhwala ndi sayansi ya zinthu.
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4-hydroxy-3,5-dimethyl-benzenecarbonitrile CAS:4198-90-7
4-Hydroxy-3,5-dimethyl-benzenecarbonitrile ndi mankhwala onunkhira okhala ndi gulu la hydroxyl, magulu awiri a methyl, ndi gulu la cyano lolumikizidwa ku mphete ya benzene. Kuphatikiza kwapadera kwa magulu ogwira ntchito kumeneku kumapereka mphamvu zapadera zamakemikolo ndi reactivity ku mankhwalawa, zomwe zimapangitsa kuti akhale ofunikira kwambiri pakugwiritsa ntchito zinthu zosiyanasiyana mu organic chemistry.
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7-Fluoroisatin CAS:317-20-4
7-Fluoroisatin ndi mankhwala opangidwa ndi heterocyclic ochokera ku isatin, omwe ali ndi atomu ya fluorine pamalo a 7 a mphete ya indole. Kusintha kumeneku kumawonjezera mphamvu zake zamagetsi komanso momwe zimagwirira ntchito. Monga membala wa banja la isatin, imasunga magwiridwe antchito a keto ndi amine, zomwe zimapangitsa kuti ikhale malo ofunikira osinthira mankhwala osiyanasiyana. Kapangidwe kake kapadera kamapangitsa kuti ikhale yofunika kwambiri pakupanga mankhwala ndi kupanga zinthu zachilengedwe.
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7-Fluorooxindole CAS: 71294-03-6
7-Fluorooxindole ndi chinthu chochokera ku fluorine chomwe chimachokera ku oxindole, chomwe chimadziwika ndi kupezeka kwa atomu ya fluorine pamalo 7 a mphete ya indole. Kusintha kumeneku kumawonjezera mphamvu zake zamagetsi ndi ntchito zake zamoyo, zomwe zimapangitsa kuti ikhale chinthu chofunikira kwambiri mu mankhwala. Kapangidwe kake kapadera ka 7-fluorooxindole kamalola kusintha kwamitundu yosiyanasiyana ya mankhwala, zomwe zimapangitsa kuti ikhale yothandiza ngati chomangira chopangira mamolekyu ovuta kwambiri.
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Chloroacetaldehyde diethyl acetal CAS:621-62-5
Chloroacetaldehyde diethyl acetal ndi mankhwala achilengedwe omwe amadziwika ndi kukhalapo kwa gulu la chloroacetaldehyde ndi magulu awiri a ethyl acetal. Mankhwalawa nthawi zambiri amakhala amadzimadzi opanda mtundu wokhala ndi fungo losiyana ndipo amagwiritsidwa ntchito ngati gawo lapakati pa kupanga mankhwala osiyanasiyana. Kapangidwe kake kamalola kuti zinthu zisinthe zomwe zingagwiritsidwe ntchito m'njira zosiyanasiyana, makamaka popanga mankhwala abwino komanso mankhwala.
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Dimecrotic acid CAS: 7706-67-4
Dimecrotic acid, yomwe imadziwikanso kuti 1,2-bis(methylthio)ethane-1,2-dicarboxylic acid, ndi mankhwala achilengedwe okhala ndi magulu awiri a carboxylic acid (-COOH) pamodzi ndi zinthu zina zolowa m'malo mwa methylthio. Mankhwalawa amadziwika ndi kapangidwe kake kosiyana, komwe kumathandizira kuti agwire ntchito bwino komanso kuti azigwira ntchito bwino m'njira zosiyanasiyana za mankhwala. Chifukwa cha magulu ake ogwira ntchito, dimecrotic acid imatha kutenga nawo mbali pazinthu zosiyanasiyana, zomwe zimapangitsa kuti ikhale yothandiza kwambiri popanga zinthu zamoyo.
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alpha,alpha'-Dichloro-p-xylene CAS:623-25-6
Alpha,alpha'-Dichloro-p-xylene ndi mankhwala onunkhira a chlorine ochokera ku p-xylene, omwe ali ndi maatomu awiri a chlorine omwe amamangiriridwa ku malo a alpha a molekyulu ya xylene. Chochokera ku dichlorine ichi chili ndi mawonekedwe apadera komanso achilengedwe omwe amachipangitsa kukhala chofunikira pakati pa njira zosiyanasiyana zamakemikolo. Kapangidwe kake kamalola kuti pakhale njira zosiyanasiyana zogwirira ntchito, zomwe zimapangitsa kuti chigwiritsidwe ntchito popanga ndi kugwiritsa ntchito mafakitale.
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4-Amino-3-nitrobenzotrifluoride CAS:400-98-6
4-Amino-3-nitrobenzotrifluoride ndi mankhwala onunkhira omwe amadziwika ndi kukhalapo kwa gulu la amino, gulu la nitro, ndi magulu atatu a trifluoromethyl olumikizidwa ku mphete ya benzene. Kuphatikiza kwapadera kwa magulu ogwira ntchito awa kumathandizira kuti akhale ndi mphamvu zapadera zamakemikolo komanso momwe amachitira zinthu. Mankhwalawa nthawi zambiri amagwiritsidwa ntchito ngati chothandizira pakupanga zinthu zosiyanasiyana, makamaka popanga mankhwala apadera komanso mankhwala.
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4,4′-Bis(hydroxymethyl)biphenyl CAS:1667-12-5
4,4′-Bis(hydroxymethyl)biphenyl ndi mankhwala achilengedwe omwe ali ndi mayunitsi awiri a biphenyl olumikizidwa ndi magulu a hydroxymethyl (-CH2OH) pamalo a para. Mankhwalawa amadziwika ndi mawonekedwe ake oyera a kristalo ndipo amadziwika ndi mawonekedwe ake ambiri. Chifukwa cha kukhalapo kwa magulu a hydroxymethyl, amatha kuchita zinthu zosiyanasiyana za mankhwala, zomwe zimapangitsa kuti ikhale yothandiza kwambiri pa ntchito zingapo zopangira.
