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2,4,5-trifluorobenzyl bromide CAS:157911-56-3
2,4,5-Trifluorobenzyl bromide ndi mankhwala achilengedwe omwe amagwira ntchito kwambiri omwe ali m'gulu la aryl halides. Kapangidwe kake ka molekyulu kamadziwika ndi mphete ya benzene yomwe imasinthidwa ndi maatomu atatu a fluorine pamalo a 2, 4, ndi 5, pamodzi ndi atomu ya bromine yolumikizidwa pamalo a benzyl. Kapangidwe kameneka kamapangitsa molekyulu kukhala ndi mphamvu yowonjezera ya electrophilic, zomwe zimapangitsa kuti ikhale reagent yofunika kwambiri mu kapangidwe ka organic.
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(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone CAS:915095-86-2
Methanone iyi (2-chloro-5-iodophenyl) (4-fluorophenyl) imadziwika ngati chinthu chofunikira kwambiri pakupanga mankhwala achilengedwe, yokhala ndi kapangidwe kake kodziwika ndi kusakanikirana kwa mphete ya benzene ndi zinthu ziwiri zosiyana zamagetsi: gulu la 2-chloro-5-iodo ndi gulu la 4-fluorophenyl. Kapangidwe kapadera kameneka kamapangitsa molekyuluyi kukhala ndi mitundu yambiri ya mankhwala, zomwe zimapangitsa kuti ikhale yofunika kwambiri pa ntchito zosiyanasiyana m'magawo azachipatala ndi sayansi ya zinthu.
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(S)-(2-Chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone CAS:915095-87-3
Methanone ya (S)-(2-chloro-5-iodophenyl)(4-(tetrahydrofuran-3-yloxy)phenyl)methanone ndi molekyulu yachilengedwe yopangidwa mwaluso yomwe imapanga magulu angapo ogwira ntchito, zomwe zimapangitsa kuti ikhale yovuta komanso yogwiritsidwa ntchito mosiyanasiyana. Kapangidwe kake kamakhala ndi mphete ya benzene yokongoletsedwa ndi zinthu ziwiri zolowa m'malo mwake: gulu la 2-chloro-5-iodo ndi gulu la 4-(tetrahydrofuran-3-yloxy)phenyl. Kapangidwe kameneka kamapangitsa kuti pakhale gulu lokhala ndi magulu opereka ndi kutulutsa ma elekitironi, zomwe zimakhudza kwambiri machitidwe ake a mankhwala.
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1-(3,5-Dichlorophenyl)-2,2,2-trifluoroethanone CAS:130336-16-2
1-(3,5-Dichlorophenyl)-2,2,2-trifluoroethanone ndi chinthu cha organochlorine chomwe chili ndi gulu la trifluoromethyl lomwe limalumikizidwa ku msana wa ethanone. Kupezeka kwa gulu la trifluoromethyl kumapereka mawonekedwe apadera ku molekyuluyi, monga kuwonjezeka kwa lipophilicity ndi kuchuluka kwa electronegativity, zomwe zingakhudze kwambiri reactivity yake ndi kukhazikika kwake.
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3-(3-iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS:148870-57-9
3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one ndi mankhwala ovuta achilengedwe omwe ali m'banja la benzazepine. Ali ndi mphete ya benzene yokhala ndi ziwalo zisanu ndi ziwiri yolumikizidwa ku mphete ya azepine yokhala ndi ziwalo zitatu, yokhala ndi magulu awiri a methoxy olumikizidwa ku malo 7 ndi 8 a mphete ya benzene. Chophatikizacho chilinso ndi unyolo wa iodoalkyl pamalo 3 a mphete ya azepine.
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7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one CAS:73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one ndi mankhwala a bicyclic omwe ali m'banja la benzazepine. Ali ndi mphete ya benzene yokhala ndi ziwalo zisanu ndi ziwiri yolumikizidwa ku mphete ya azepine yokhala ndi ziwalo zitatu, yokhala ndi magulu awiri a methoxy olumikizidwa ku malo a 7 ndi 8 a mphete ya benzene. Mankhwalawa alinso ndi gulu la ketone lomwe lili pamalo a 2 a mphete ya azepine.
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![(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride CAS:866783-13-3](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG275.png)
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride CAS:866783-13-3
(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride ndi chinthu chachilengedwe cha chiral chomwe chili ndi pakati pa benzocyclobutane ndi magulu awiri a methoxy olumikizidwa ku malo 4 ndi 5 a mphete ya cyclobutane. Chophatikizacho chilinso ndi gulu la methylamino lolumikizidwa ku malo 1 a mphete ya cyclobutane, yomwe imapanga chomangira chowonjezera cha carbon-nitrogen.
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Naphthalene, 1-cyclopropyl-4-isothiocyanato- CAS:878671-95-5
Naphthalene, 1-cyclopropyl-4-isothiocyanato- ndi chinthu chochokera ku naphthalene, polycyclic aromatic hydrocarbon yokhala ndi mphete ziwiri za benzene zosakanikirana. Mu chinthu chochokera ichi, gulu la cyclopropyl limalumikizidwa ku malo amodzi a naphthalene core, pomwe gulu la isothiocyanato limalumikizidwa ku malo anayi.
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3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro CAS:878671-96-6
3H-1,2,4-Triazole-3-thione, 5-amino-4-[4-cyclopropyl-1-naphthalenyl]-2,4-dihydro, yomwe imadziwika kuti 5-amino-4-[4-cyclopropyl-1-naphthalenyl]-1,2,4-triazole-3-thione kapena kungoti TTTA, ndi chinthu chopangidwa ndi heterocyclic chomwe chili ndi pakati pa triazole cholumikizidwa ndi mphete ya naphthalene. Mphete ya triazole ndi mphete yokhala ndi ziwalo zisanu yokhala ndi maatomu atatu a nayitrogeni, pomwe mphete ya naphthalene ndi mphete yokhala ndi ziwalo zisanu ndi chimodzi yolumikizidwa ndi mphete yachiwiri ya benzene.
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Losartan CAS:114798-26-4
Losartan ndi mankhwala ochepetsa kuthamanga kwa magazi omwe ali m'gulu la angiotensin II receptor blockers (ARBs). Amagwira ntchito poletsa ntchito ya angiotensin II, vasoconstrictor yamphamvu yomwe imagwira ntchito yofunika kwambiri pakulamulira kuthamanga kwa magazi. Mwa kuletsa kumangirira kwa angiotensin II ku ma receptor ake, losartan imachepetsa vasoconstriction ndikuchepetsa kutulutsidwa kwa aldosterone, mahomoni omwe amagwira ntchito pakusunga sodium ndi madzi m'thupi.
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(1R,2R)-1,2-Cyclohexanedimethanol CAS:65376-05-8
Losartan ndi mankhwala ochepetsa kuthamanga kwa magazi omwe ali m'gulu la angiotensin II receptor blockers (ARBs). Amagwira ntchito poletsa ntchito ya angiotensin II, vasoconstrictor yamphamvu yomwe imagwira ntchito yofunika kwambiri pakulamulira kuthamanga kwa magazi. Mwa kuletsa kumangirira kwa angiotensin II ku ma receptor ake, losartan imachepetsa vasoconstriction ndikuchepetsa kutulutsidwa kwa aldosterone, mahomoni omwe amagwira ntchito pakusunga sodium ndi madzi m'thupi.
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Asidi ya Acetic, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, ethyl ester CAS:1158970-52-5
Acetic acid, 2-((5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl)thio)-, ethyl ester ndi chinthu chovuta chachilengedwe chomwe chimakhala ndi acetic acid ester yomwe imagwira ntchito ndi mphete ya 1,2,4-triazole ndi gawo la naphthalene losinthidwa ndi cyclopropyl. Mphete ya triazole ndi mphete ya heterocyclic yokhala ndi ziwalo zisanu yokhala ndi maatomu atatu a nayitrogeni, pomwe mphete ya naphthalene ndi mphete ya zonunkhira yokhala ndi ziwalo zisanu ndi chimodzi yolumikizidwa ku mphete yachiwiri ya benzene.
