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2-Hydroxyisonicotinic acid CAS: 90-33-5
2-Hydroxysonicotinic acid ndi yochokera ku isonicotinic acid, yomwe imadziwika ndi kukhalapo kwa gulu la hydroxyl pamalo achiwiri a mphete ya pyridine. Chomerachi chimasonyeza ntchito zosiyanasiyana zamoyo, kuphatikizapo mphamvu zotsutsana ndi mabakiteriya komanso zotsutsana ndi kutupa. Kufanana kwake ndi kapangidwe kake ndi zinthu zina zochokera ku nicotinic acid kumapangitsa kuti chikhale cholinga chosangalatsa pakupanga mankhwala. Ofufuza akhala akufufuza momwe amagwiritsidwira ntchito mu mankhwala, makamaka pochiza matenda osiyanasiyana. Chomerachi chimagwira ntchito ngati chomangira kupanga mamolekyu ovuta kwambiri ndipo chakopa chidwi m'magawo a organic synthesis ndi kafukufuku wamankhwala.
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Methyl 2-aminopyridine-4-carboxylate CAS:6937-03-7
Methyl 2-aminopyridine-4-carboxylate ndi chinthu chochokera ku pyridine chomwe chili ndi gulu la amino pamalo a 2 ndi ester ya carboxylate pamalo a 4, ndipo gulu la methyl limalumikizidwa ndi carboxylic acid. Chomerachi chili ndi chidwi ndi mankhwala chifukwa cha ntchito zake zamoyo, kuphatikizapo mphamvu zotsutsana ndi mavairasi komanso zotsutsana ndi kutupa. Kapangidwe kapadera ka magulu ogwira ntchito kamawonjezera mphamvu zake komanso kugwiritsidwa ntchito kwake ngati chinthu chomangira chosiyanasiyana mu kapangidwe ka organic. Kafukufuku akupitiliza kufufuza momwe amagwiritsidwira ntchito popanga mankhwala ndi madera ena, kusonyeza kufunika kwake mkati mwa heterocyclic chemistry.
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Tofacitinib Citrate CAS:540737-29-9
Tofacitinib citrate ndi mankhwala oletsa Janus kinase (JAK) omwe amagwiritsidwa ntchito makamaka pochiza nyamakazi, nyamakazi ya psoriatic, ndi matenda a ulcerative colitis. Imagwira ntchito poletsa ma enzyme a JAK1 ndi JAK3, omwe amagwira ntchito yofunika kwambiri pakupereka zizindikiro za ma cytokines osiyanasiyana omwe amakhudzidwa ndi kutupa. Ndi formula ya molekyulu C16H20N6O5S·C6H8O7, tofacitinib citrate yawonetsa kuti imagwira ntchito bwino pochepetsa kutupa ndikukweza moyo wa wodwala. Yavomerezedwa kuti igwiritsidwe ntchito kuchipatala m'maiko angapo, kafukufuku wopitilira akufuna kufufuza momwe imagwirira ntchito pochiza matenda osiyanasiyana, chitetezo, komanso zotsatira zake za nthawi yayitali m'matenda osiyanasiyana a autoimmune.
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Cyclen CAS:294-90-6
Cyclen, kapena 1,4,7,10-tetraazacyclododecane, ndi mankhwala a polyamine odziwika bwino chifukwa cha kapangidwe kake kapadera ka cyclic komwe kali ndi ma atomu anayi a nayitrogeni omwe amaphatikizidwa mu mphete yokhala ndi ziwalo khumi ndi ziwiri. Ndi formula ya molekyulu C8H16N4, cyclen imagwira ntchito ngati ligand yofunika kwambiri mu chemistry yolumikizana chifukwa cha kuthekera kwake kupanga ma complexes okhazikika ndi zitsulo zosinthika. Kapangidwe kake ka chelating kamapangitsa kuti ikhale yofunikira pa ntchito zosiyanasiyana, kuphatikiza chemistry yamankhwala, radiopharmaceuticals, ndi supramolecular chemistry. Kafukufuku wopitilira akufufuza kuthekera kwa cyclen m'machitidwe operekera mankhwala ndi chitukuko cha othandizira kujambula zithunzi, kugogomezera kufunika kwake mu sayansi yoyambira komanso yogwiritsidwa ntchito.
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![4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT317.png)
4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5
4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane ndi mankhwala a bicyclic organic omwe amadziwika ndi kapangidwe kake kapadera komwe kali ndi ma ether linkages awiri ndi ma atomu atatu a okosijeni mkati mwa chimango cha bicyclic. Ndi formula ya molekyulu C10H16O3, mankhwalawa amasonyeza zinthu zosangalatsa chifukwa cha kukhalapo kwa magulu a methyl ndi ntchito za ether. Kapangidwe kake ka bicyclic kamathandizira kukhazikika kwake ndi reactivity yake, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito m'njira zosiyanasiyana mu organic chemistry yopangidwa. Kafukufuku akufufuza momwe imagwiritsidwira ntchito popanga mamolekyu ovuta kwambiri komanso kuthekera kwake ngati chomangira mu sayansi ya zamankhwala ndi zinthu.
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![4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M290.png)
4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1
4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine ndi mankhwala opangidwa omwe amadziwika bwino chifukwa cha ntchito zake zamankhwala. Ali ndi kapangidwe kake kapadera komwe kali ndi pyrrolopyrimidine core, chloro substituent, ndi sulfonyl moiety yolumikizidwa ndi gulu la para-methylphenyl. Kapangidwe kameneka kangathandize pa ntchito yake yachilengedwe, zomwe zimapangitsa kuti ikhale yoyenera kufufuza m'madera monga khansa kapena kutupa. Kafukufuku akuchitika kuti afufuze njira zake zogwirira ntchito, mphamvu zake, komanso chitetezo chake, ndi cholinga chofuna kudziwa momwe angagwiritsire ntchito pochiza matenda osiyanasiyana.
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3-Pyridinesulfonyl chloride CAS:16133-25-8
3-Pyridinesulfonyl chloride ndi chinthu chofunikira kwambiri chachilengedwe chokhala ndi formula ya molekyulu C6H6ClN O2S. Ndi sulfonyl chloride yochokera ku pyridine, yokhala ndi gulu la sulfonyl chloride lomwe limalumikizidwa pamalo achitatu a mphete ya pyridine. Chomerachi chimagwiritsidwa ntchito makamaka mu kapangidwe ka organic ngati reagent yolowetsa magulu a sulfonyl m'magulu osiyanasiyana. Kugwira ntchito kwake kumalola kuti igwire nawo ntchito mu ma nucleophilic substitution reactions, zomwe zimapangitsa kuti ikhale yofunika kwambiri popanga sulfonamides ndi mamolekyu ena ogwira ntchito. Kuphatikiza apo, 3-pyridinesulfonyl chloride imatha kugwiritsidwa ntchito mu mankhwala ndi mankhwala a agrochemicals.
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2-Aminoisonicotinic acid CAS: 13362-28-2
2-Aminoisonicotinic acid ndi chochokera ku pyridine, makamaka isomer ya nicotinic acid, yomwe imadziwika ndi kukhalapo kwa gulu la amino pamalo awiri a mawonekedwe a isonicotinic acid. Ndi formula ya molekyulu C6H6N2O2, chigawochi chikuwonetsa zinthu zosangalatsa zamakemikolo ndipo chakopa chidwi mu chemistry yamankhwala chifukwa cha ntchito zake zamoyo, kuphatikizapo mphamvu zotsutsana ndi maantibayotiki ndi zotsutsana ndi kutupa. Ntchito za amino ndi carboxylic acid zimathandiza kusintha kwamitundu yosiyanasiyana yamakemikolo, zomwe zimapangitsa kuti ikhale yothandiza kwambiri popanga zinthu zachilengedwe. Kafukufuku wopitilira akufufuza mphamvu zake zochiritsira, kuwonetsa kufunika kwake pakupanga mankhwala ndi ntchito zina.
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2-Amino-4-cyanopyridine CAS:42182-27-4
2-Amino-4-cyanopyridine ndi chinthu chochokera ku pyridine chomwe chimadziwika ndi gulu la amino pamalo a 2 ndi gulu la cyano pamalo a 4 a mphete ya pyridine. Ndi fomula ya molekyulu C6H4N4, chinthuchi chimasonyeza zinthu zodabwitsa za mankhwala komanso zochita zamoyo. Chaphunziridwa chifukwa cha ntchito zake mu chemistry yamankhwala, makamaka pakupanga mankhwala chifukwa cha mphamvu zake zotsutsana ndi mabakiteriya, bowa, komanso zotsutsana ndi kutupa. Kupezeka kwa magulu onse awiri ogwira ntchito kumawonjezera mphamvu zake, zomwe zimapangitsa kuti chikhale chofunikira kwambiri popanga zinthu zachilengedwe. Kafukufuku akupitiliza kufufuza momwe chimagwirira ntchito m'magawo osiyanasiyana kuphatikiza mankhwala ndi mankhwala a agrochemicals.
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2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) CAS:399017-10-8
2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, ethyl ester, hydrochloride (1:1) ndi chinthu chochokera ku thiazole, chomwe chimadziwika ndi kapangidwe kake kapadera komwe kamaphatikizapo gulu la hydroxyl, gulu la methyl, ndi ethyl ester. Chomerachi chapeza chidwi ndi mankhwala chifukwa cha ntchito zake zamoyo, monga mphamvu zotsutsana ndi kutupa komanso maantibayotiki. Mchere wa hydrochloride umawonjezera kusungunuka ndi kukhazikika, zomwe zimathandiza kuti ugwiritsidwe ntchito m'njira zopangira mankhwala. Kafukufuku akupitiliza kufufuza momwe umagwirira ntchito pochiza matenda osiyanasiyana, zomwe zimapangitsa kuti ukhale wofunikira kwambiri pa maphunziro ena pakupanga mankhwala ndi kukonza bwino lead.
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3-Methyl-4-nitropyridine N-Oxide CAS:1074-98-2
3-Methyl-4-nitropyridine N-oxide ndi chinthu chochokera ku pyridine chomwe chimadziwika ndi gulu la methyl pamalo a 3 ndi gulu la nitro pamalo a 4 a mphete ya pyridine, pamodzi ndi gulu logwira ntchito la N-oxide. Chomerachi chimasonyeza makhalidwe abwino a mankhwala ndi zochita zamoyo, zomwe zimapangitsa kuti chikhale chosangalatsa m'magawo osiyanasiyana monga mankhwala ndi mankhwala a agrochemicals. Kupezeka kwa magulu onse a nitro ndi N-oxide kungathandize kukulitsa reactivity yake ndi ntchito zake zomwe zingatheke mu mankhwala opangidwa. Kafukufuku akupitiliza kufufuza momwe chomerachi chimagwirira ntchito popeza mankhwala ndi ntchito zina, kusonyeza kufunika kwake mu mankhwala achilengedwe amakono.
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(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine CAS:511534-44-4
(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine ndi chinthu chofunikira cha chiral chomwe chili ndi gulu la sulfonamide functional ndi diphenylethylene backbone. Ndi molecular formula C16H20N2O2S, chinthuchi chimagwira ntchito yofunika kwambiri pakupanga ndi catalysis yosagwirizana chifukwa cha kuthekera kwake kupanga malo okhazikika a chiral. Kapangidwe kake kapadera kamalola kuti pakhale zochita zosankhidwa, zomwe zimapangitsa kuti zikhale zofunikira pakupanga mankhwala ndi mankhwala a agrochemicals. Kafukufuku wopitilira akufufuza momwe amagwiritsidwira ntchito pakupanga stereoselective, kuwonetsa kuthekera kwake ngati ligand mu organometallic chemistry ndikukulitsa kufunika kwake mu synthesis yamakono ya organic.
