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Cytidine-5′-monophosphate (CMP), asidi waulere CAS:63-37-6
Cytidine 5'-monophosphate (CMP) ndi nucleotide yomwe imagwira ntchito ngati chimango cha kapangidwe ndi kusintha kwa RNA. Ndi gawo lofunikira kwambiri popanga mamolekyu a RNA ndipo limakhudzidwa ndi njira monga mRNA capping ndi nucleotide metabolism. CMP imagwiritsidwanso ntchito mu kafukufuku wa biochemical ndi molecular biology pazinthu monga in vitro transcription ndi nucleic acid labeling. Udindo wake mu RNA metabolism ndi kugwiritsidwa ntchito kwake m'njira zosiyanasiyana zoyesera zimapangitsa kuti ikhale chida chofunikira kwambiri pakumvetsetsa kapangidwe ndi ntchito ya mamolekyu a RNA.
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IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4
3-isobutyl-1-methylxanthine, yomwe imadziwikanso kuti IBMX, ndi mankhwala ochokera ku methylxanthine omwe amagwiritsidwa ntchito kwambiri mu kafukufuku wa sayansi ngati choletsa chosadziwika bwino cha cyclic nucleotide phosphodiesterases. Amadziwika kuti amawonjezera kuchuluka kwa cyclic AMP (cAMP) ndi cyclic GMP (cGMP) mkati mwa maselo mwa kuletsa kuwonongeka kwawo, zomwe zimatha kusintha njira zosiyanasiyana zolumikizirana ndi maselo.
Kuwonjezera pa ntchito zake zofufuza, IBMX yagwiritsidwa ntchito m'malo ena azachipatala chifukwa cha mphamvu zake zochepetsera kutupa ndi kutsekereza mitsempha yamagazi. Komabe, kugwiritsidwa ntchito kwake mu mankhwala a anthu ndi kochepa.
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4-Nitrophenyl phosphate disodium salt hexahydrate CAS:4264-83-9
4-Nitrophenyl phosphate disodium salt hexahydrate ndi mankhwala omwe amagwiritsidwa ntchito nthawi zambiri pofufuza zamankhwala ndi zamankhwala. Ndi mchere wa 4-nitrophenyl phosphate, womwe uli ndi ma ayoni awiri a sodium ndi mamolekyu asanu ndi limodzi amadzi. Mankhwalawa amagwiritsidwa ntchito kwambiri ngati gawo loyesera phosphatase komanso pophunzira za kinetics ya enzyme.
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5′-Deoxy-5-fluorocytidine CAS:66335-38-4
5′-Deoxy-5-fluorocytidine ndi mankhwala opangidwa ndi nucleoside omwe akufufuzidwa chifukwa cha mphamvu yake yolimbana ndi mavairasi, makamaka motsutsana ndi mavairasi a RNA monga kachilombo ka hepatitis C (HCV) ndi mavairasi a flavi. Imagwira ntchito posokoneza kubwerezabwereza kwa majini a mavairasi, zomwe pamapeto pake zimalepheretsa kachilomboka kuchulukana ndikufalikira m'thupi.
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Cytidine-5′-triphosphate (CTP), mchere wa disodium CAS:652154-13-7
Mchere wa disodium wa Cytidine-5′-triphosphate (CTP) ndi nucleoside triphosphate yomwe imagwira ntchito ngati chomangira cha kapangidwe ka RNA. Imagwira ntchito yofunika kwambiri pa kagayidwe ka maselo ndipo ndiyofunikira pakusintha kwa chidziwitso cha majini kuchokera ku DNA kupita ku RNA panthawi yolemba. CTP imagwiritsidwa ntchito kwambiri mu kafukufuku wa biology ya mamolekyulu, makamaka mu maphunziro okhudzana ndi kapangidwe ka RNA, kulowerera kwa RNA, ndi njira zina zokhudzana ndi RNA. Kuphatikiza apo, imagwiritsidwa ntchito mu zochita za enzyme, maphunziro a kagayidwe ka nucleotide, komanso ngati gawo la mayeso osiyanasiyana a biochemical. Mumakampani opanga mankhwala, CTP ingagwiritsidwenso ntchito popanga mankhwala oletsa mavairasi ndi khansa.
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ITP, inosine 5′-triphosphate trisodium salt CAS:35908-31-7
Mchere wa Inosine-5′-triphosphate triphosphate trisodium, womwe nthawi zambiri umafupikitsidwa kuti ITP-Na3, ndi mtundu wa triphosphate wa inosine, nucleoside yomwe imagwira ntchito yofunika kwambiri m'njira zosiyanasiyana zamoyo. Chomerachi ndi chamchere, chomwe chimachipangitsa kuti chisungunuke m'madzi ndipo chigwiritsidwe ntchito poyesa za biochemical ndi enzymatic, komanso kafukufuku wa biology ya mamolekyulu. Mchere wa Inosine-5′-triphosphate trisodium umagwiritsidwa ntchito pophunzira momwe enzymatic imagwirira ntchito, kusinthasintha kwa nucleotide, komanso ngati gawo la ma enzyme ena. Kugwiritsa ntchito kwake kumakhudzanso maphunziro a analog a nucleotide komanso ngati gawo lokonzekera zosakaniza za nucleotide zomwe zimagwiritsidwa ntchito mu njira za biology ya mamolekyulu.
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5-Bromouracil CAS: 51-20-7 Mtengo wa Wopanga
5-Bromouracil ndi chinthu chofanana ndi uracil, chomwe ndi gawo la RNA. 5-Bromouracil ikhoza kuyikidwa mu nucleic acids ndipo ingayambitse kusintha kwa majini mwa kusalumikizana bwino ndi guanine panthawi yobwerezabwereza kwa DNA. Imagwiritsidwa ntchito ngati mutagen mu kafukufuku wa majini kuti iphunzire kuchuluka kwa kusintha kwa majini ndi njira zake.
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5-Fluoro-2′-deoxyuridine CAS:50-91-9
5-Fluoro-2′-deoxyuridine ndi mankhwala opangidwa ndi nucleoside omwe amaletsa kupanga DNA. Afufuzidwa kuti adziwe ngati ali ndi mphamvu zotsutsana ndi mavairasi komanso zotsutsana ndi chotupa. Kuphatikiza apo, amagwiritsidwa ntchito ngati chida chofufuzira mu sayansi ya zamoyo ndi biochemistry.
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Cytidine-5′-triphosphate disodium salt CAS:36051-68-0
Mchere wa Cytidine-5′-triphosphate disodium (CTP-Na2) ndi nucleoside triphosphate yomwe imagwira ntchito ngati chomangira popanga RNA. Imagwira ntchito yofunika kwambiri mu kagayidwe ka maselo, imagwira ntchito ngati gawo la ma RNA polymerases mu transcription komanso ngati gwero la mphamvu pazochitika zosiyanasiyana za enzyme. CTP-Na2 nthawi zambiri imagwiritsidwa ntchito mu kafukufuku wa biochemical ndi molecular biology monga gawo la zochitika zokhudzana ndi kupanga, kusintha, ndi kuwongolera RNA. Mchere wake wa disodium umawonjezera kusungunuka kwake mumadzi amadzi, zomwe zimapangitsa kuti zikhale zosavuta kugwiritsa ntchito mu labotale.
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Ribonucleic acid kuchokera ku Baker's Yeast CAS:63231-63-0
Ribonucleic acid (RNA) yochokera ku yisiti ya Baker, yomwe imadziwikanso kuti Saccharomyces cerevisiae, imatanthauza mamolekyu a RNA omwe ali mu bowa wodziwika bwino wa selo limodzi. Imagwira ntchito zosiyanasiyana zofunika mu selo, kuphatikizapo kupanga mapuloteni, ntchito ya enzymatic, ndi malamulo a majini. RNA yochokera ku yisiti ya Baker ndi yosangalatsa kwa asayansi ndi ofufuza omwe amaphunzira za sayansi ya mamolekyu, majini, ndi njira zamaselo. Imagwiritsidwa ntchito m'mayesero ndi maphunziro osiyanasiyana kuti apeze chidziwitso cha momwe majini amagwirira ntchito, kukonza RNA, ndi njira zamamolekyu zomwe zimayang'anira ntchito zamaselo.
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6-Chloropurine CAS: 87-42-3 Mtengo wa Wopanga
6-Chloropurine ndi mankhwala ochokera m'banja la purine. Ndi mankhwala ochokera ku purine, omwe ndi chinthu chofunikira kwambiri chomwe chimapanga DNA ndi RNA. 6-Chloropurine imagwiritsidwa ntchito popanga zinthu zachilengedwe komanso kafukufuku wamankhwala ngati njira yokonzekera mitundu yosiyanasiyana ya purine ndi mankhwala.
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Adenosine 5′-monophosphate disodium salt CAS:4578-31-8
Mchere wa Adenosine 5′-monophosphate disodium, womwe umadziwikanso kuti 5′-AMP, ndi nucleotide yokhala ndi adenine, ribose, ndi gulu la phosphate. Umagwira ntchito ngati choyambira cha adenosine triphosphate (ATP), yomwe ndi molekyu yofunika kwambiri yomwe imakhudzidwa ndi kusamutsa mphamvu zamaselo. Mu kafukufuku ndi ntchito zama biochemical, 5′-AMP imagwiritsidwa ntchito ngati gawo la zochita za enzyme, makamaka mu maphunziro a kagayidwe ka nucleotide, njira zolumikizirana, komanso ngati gawo la mayeso osiyanasiyana. Mchere wake wa disodium umawonjezera kusungunuka kwake ndi kukhazikika kwake, zomwe zimapangitsa kuti ugwiritsidwe ntchito poyesa.
