Fmoc-Cys(But)-OH CAS:67436-13-9

Fmoc-Cys(But)-OH imagwira ntchito ngati chida chofunikira kwambiri popanga ma peptide, makamaka popanga ma peptide okhala ndi cysteine ​​​​mwanzeru. Gulu loteteza la Fmoc limateteza gulu la amino, kuonetsetsa kuti pali zochita zosiyanasiyana panthawi yolumikizana ndi peptide, pomwe gulu la butyl limawonjezera chitetezo china ku gulu la thiol. Ofufuza amagwiritsa ntchito kwambiri Fmoc-Cys(But)-OH popanga ma peptide pazinthu zosiyanasiyana, kuphatikiza kupanga mankhwala opangidwa ndi peptide, bioconjugation, komanso kupanga ma peptide okhala ndi mawonekedwe enaake. Kugwirizana kwake ndi njira zodziwika bwino zopangira ma peptide, mu njira zonse ziwiri zokhazikika komanso zothetsera mavuto, kumawonjezera kusinthasintha kwake muzochita zosiyanasiyana zofufuzira. Kuchotsa magulu oteteza kumalola kuphatikiza kwa cysteine ​​​​m'njira za peptide, kukulitsa mitundu ya ma peptide opangidwa. Kuphatikiza apo, Fmoc-Cys(But)-OH imagwiritsa ntchito pophunzira za kupindika kwa mapuloteni, kupanga ma bond a disulfide, komanso kupanga zinthu zopangidwa ndi peptide. Kugwiritsa ntchito bwino gulu loteteza butyl kumathandiza kusintha molondola momwe cysteine ​​imagwirira ntchito, zomwe zimapatsa ofufuza chida chofunikira popanga ma peptide okhala ndi zosintha zomwe zakonzedwa. Mwachidule, Fmoc-Cys(But)-OH ndi chida chogwiritsidwa ntchito mosiyanasiyana komanso chofunikira kwambiri mu peptide chemistry, zomwe zimapatsa ofufuza mphamvu zofufuzira ndikusintha momwe cysteine ​​imagwirira ntchito pazambiri zasayansi, makamaka kuyang'ana kwambiri ma peptide omwe ali ndi amino acid yofunikayi.