Fmoc-D-Asp(OBut)-OH CAS:112883-39-3

Fmoc-D-Asp(OBut)-OH imagwira ntchito ngati gawo lofunikira kwambiri pakupanga ma peptide, makamaka popanga ma peptide okhala ndi D-enantiomer ya aspartic acid molondola. Gulu loteteza la Fmoc limateteza gulu la amino, kuonetsetsa kuti pali zochita zosiyanasiyana panthawi yolumikizana ndi peptide, pomwe gulu la O-butyl limawonjezera chitetezo china ku gulu la carboxyl. Ofufuza amagwiritsa ntchito kwambiri Fmoc-D-Asp(OBut)-OH popanga ma peptide osiyanasiyana, kuphatikiza kupanga mankhwala, zinthu zachilengedwe, komanso kupanga ma peptide ogwira ntchito omwe ali ndi mawonekedwe apadera. Kugwirizana kwake ndi njira zodziwika bwino zopangira ma peptide, mu njira zonse zokhazikika komanso zothetsera mavuto, kumawonjezera kusinthasintha kwake muzochita zosiyanasiyana zofufuzira. Kuchotsa magulu oteteza kumalola kuphatikiza kwa D-aspartic acid mu ma peptide, kukulitsa mitundu ya ma peptide opangidwa. Kuphatikiza apo, Fmoc-D-Asp(OBut)-OH imagwiritsa ntchito popanga ma peptide ofufuza ma proteomics ndikuphunzira njira zamaselo. Kugwiritsa ntchito bwino gulu loteteza la O-butyl kumathandiza kusintha molondola momwe D-aspartic acid imagwirira ntchito, zomwe zimapatsa ofufuza chida chofunikira popanga ma peptide okhala ndi zosintha zomwe zakonzedwa. Mwachidule, Fmoc-D-Asp(OBut)-OH ndi chida chogwiritsidwa ntchito mosiyanasiyana komanso chofunikira kwambiri mu peptide chemistry, zomwe zimapatsa ofufuza mphamvu zofufuzira ndikusintha momwe D-aspartic acid imagwirira ntchito m'njira zosiyanasiyana zasayansi, makamaka kuyang'ana kwambiri ma peptide omwe ali ndi amino acid yofunikayi.