Fmoc-Glu(But)-NH2 CAS:104090-92-8

Fmoc-Glu(But)-NH2 imagwira ntchito ngati chida chosiyanasiyana popanga ma peptide, zomwe zimapatsa ofufuza mphamvu yophatikiza glutamic acid ndi kuwongolera kolondola komanso kusinthasintha. Gulu loteteza la Fmoc limateteza gulu la amino, kuonetsetsa kuti pali zochita zosiyanasiyana panthawi yolumikizana ndi peptide, pomwe gulu la butyl limawonjezera chitetezo china ku gulu la carboxyl. Ofufuza amagwiritsa ntchito kwambiri Fmoc-Glu(But)-NH2 popanga ma peptide pazinthu zosiyanasiyana, kuphatikiza kapangidwe ka peptide mimetics, peptide conjugation, ndi chitukuko cha ma peptides a bioactive. Gulu la amino limalola magwiridwe antchito ena, zomwe zimathandiza kuti mamolekyu osiyanasiyana, ma fluorophores, kapena zinthu zina zigwirizane ndi mawonekedwe a ma peptide opangidwa. Kuphatikiza apo, Fmoc-Glu(But)-NH2 imapeza phindu m'maphunziro okhudzana ndi chitukuko cha mankhwala opangidwa ndi peptide, chifukwa gulu loteteza butyl limakulitsa kukhazikika ndi kutulutsidwa kolamulidwa kwa glutamic acid yophatikizidwa. Kugwirizana kwake ndi njira zodziwika bwino zopangira ma peptide, mu njira zonse ziwiri zokhazikika komanso zothetsera mavuto, kumawonjezera kusinthasintha kwake m'mayesero osiyanasiyana ofufuza. Mwachidule, Fmoc-Glu(But)-NH2 ndi chida chofunikira komanso chofunikira kwambiri mu chemistry ya peptide, chomwe chimapatsa ofufuza njira zosiyanasiyana zopangira ma peptide opangidwa ndi anthu omwe ali ndi ntchito zinazake, makamaka kuyang'ana kwambiri ma peptide omwe ali ndi glutamic acid.