Fmoc-Tyr(But)-OSu CAS:155892-27-6

Fmoc-Tyr(But)-OSu imagwira ntchito ngati reagent yofunika kwambiri pakupanga ma peptide, makamaka pakusintha kosankha kwa mapuloteni ndi ma peptide. Ntchito ya OSu ester imalola kulumikizana bwino kwa tyrosine ndi mamolekyu okhala ndi amine kapena othandizira olimba, zomwe zimathandiza kuyambitsa zotsalira za tyrosine pamalo enaake mkati mwa peptide sequence. Gulu la Fmoc likhoza kuchotsedwa pansi pamikhalidwe yofatsa kuti liwonetse reactive OSu ester, zomwe zimathandiza kuti pakhale ma conjugation reaction. Kuphatikiza apo, Fmoc-Tyr(But)-OSu imagwiritsa ntchito kwambiri njira za bioconjugation popanga ma conjugates a mapuloteni ndi mankhwala, ma peptide-based imaging probes, ndi ma vaccine constructs. Kugwirizana kwake ndi solid-phase peptide synthesis kumathandiza kupanga ma conjugates a peptide apadera omwe amapangidwira ntchito zosiyanasiyana zamankhwala, kuphatikiza kupereka mankhwala ndi zida zodziwira matenda. Mwachidule, Fmoc-Tyr(But)-OSu imagwira ntchito yofunika kwambiri pakupititsa patsogolo kafukufuku wa bioconjugation ndi peptide chemistry, kupatsa mphamvu asayansi ndi ofufuza kuti apange ma conjugates ndi ma peptide atsopano omwe ali ndi njira zochiritsira, zodziwira matenda, komanso zofufuzira.