Gabapentin CAS: 60142-96-3 Wopanga Wopanga

Gabapentin ndi amino acid yogwirizana ndi γ-Aminobutyric Acid (GABA), yopangidwa kuti idutse chotchinga chaubongo.Amagwiritsidwa ntchito ngati anticonvulsant.Amaperekedwanso kwa odwala ambiri omwe ali ndi sclerosis kuti athe kuwongolera ma dysesthesia ndipo atha kukhala othandiza kuchepetsa ululu wa neuropathic chifukwa cha khansa ndi kachilombo ka HIV.Simangirira ku GABA zolandilira, sizimakhudza kutengeka kwa neural kwa GABA, ndipo siziletsa GABA-metabolizing enzyme, GABA transaminase.Mosiyana ndi GABA, yomwe sidutsa chotchinga cha magazi ndi ubongo, gabapentin imalowa mkati mwa mitsempha yapakati ndikumangiriza ku njira za α2δ-mtundu wa voltage-gated calcium.Limagwirira kwa analgesic ndi anticonvulsant zotsatira za gabapentin sizidziwika.