Leflunomide CAS: 75706-12-6 Wopanga Wogulitsa

Leflunomide ndi mankhwala ochepetsa ululu wa mano omwe amapezeka pakamwa ndipo adayambitsidwa ku US ngati Arava pochiza matenda a nyamakazi (RA); ndi mankhwala oyamba komanso okhawo omwe awonetsedwa kuti achepetse kuwonongeka kwa mafupa a RA, motero kuthana ndi zosowa zachipatala zomwe sizinakwaniritsidwe. Leflunomide ndi mankhwala omwe amasinthidwa mwachangu komanso pafupifupi kwathunthu (theka la moyo,

Oda kapena Pemphani Mtengo

Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Kugwiritsa Ntchito ndi Zotsatira zake

Leflunomide sigwira ntchito, koma teriflunomide imaletsa kupanga pyrimidine de novo pa mlingo wochepa wa mankhwala mwa kuletsa dihydroorotate dehydrogenase (enzyme yomwe imayesa kuchuluka kwa UMP), kuchepetsa kupanga DNA ndi RNA, ndikuletsa kuchulukana kwa maselo ndi kupanga ma antibodies. Kuchepa kwa dihydroorotate kukhala orotate kumachitika nthawi imodzi ndi kuchepa kwa cofactor yake, ubiquinone (coenzyme Q). Kuletsa dihydroorotate dehydrogenase ndi teriflunomide kumasonyeza kuti kinetics yake si yopikisana komanso yosapikisana. Kupereka leflunomide kwa odwala omwe ali ndi nyamakazi ya rheumatoid kumapangitsa kuti maselo a B achotsedwe pang'onopang'ono ndikuchepetsa chitetezo cha mthupi.

Chitsanzo cha Zamalonda

Kulongedza Zinthu:

Zina Zowonjezera:

Kapangidwe kake	C12H9F3N2O2
Kuyesa	99%
Maonekedwe	Ufa woyera
Nambala ya CAS	75706-12-6
Kulongedza	25KG
Moyo wa Shelufu	zaka 2
Malo Osungirako	Sungani pamalo ozizira komanso ouma
Chitsimikizo	ISO.