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Letrozole CAS: 112809-51-5 Wopanga Manufacturer

Letrozole ndi gawo la m'badwo watsopano wa aromatase inhibitors omwe amasankha kwambiri ndipo ndi wopangidwa mwaluso wopangidwa ndi benzotriazole.Letrozole amaletsa aromatase kuti achepetse misinkhu ya estrogen, motero amalepheretsa estrogen kuti asalimbikitse kukula kwa chotupa.Ntchito yake mu vivo ndi mphamvu 150-250 kuposa ya m'badwo woyamba aromatase inhibitor Amarante.Chifukwa chosankha kwambiri, sichidzakhudza glucocorticoid, mineralocorticoid ndi ntchito za chithokomiro;ngakhale pa mlingo waukulu, sizikhala ndi zotsatira zolepheretsa kutulutsa kwa adrenal corticosteroid, kuwapatsa chiwerengero chachikulu cha mankhwala.


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Zogulitsa Tags

Kugwiritsa Ntchito ndi Zotsatira

Letrazole ikhoza kupangidwa muzitsulo ziwiri kuchokera ku 4- bromomethyl-benzonitrile ndi 1,2,4-triazole ndipo ndi m'badwo wachitatu wa aromatase inhibitor.Ndi inhibitor yeniyeni ya P450arom yomwe imalepheretsa kutembenuka kwa androstenedione kukhala estrone.Kuchepetsa kwa plasma estrogen kunali kofulumira komanso kwanthawi yayitali.Izi zimatheka popanda kulepheretsa zina za steroid biosynthesis zomwe zimapangitsa kuti aromatase inhibitor ikhale yosankhidwa kwambiri.Letrazole ali ndi antitumor yodabwitsa, amalekerera bwino ndipo alibe zotsatirapo zoyipa.Ndi mphamvu 10,000 kuposa aminoglutethimide, mu vivo, choyamba chokhazikitsidwa bwino cha aromatase inhibitor.

Product Chitsanzo

图片290(1)
Chithunzi cha 222(1)

Kulongedza katundu:

Chithunzi cha 198(1)

Zina Zowonjezera:

Kupanga C17H11N5
Kuyesa 99%
Maonekedwe White ufa
CAS No. 112809-51-5
Kulongedza 25KG
Shelf Life zaka 2
Kusungirako Sungani pamalo ozizira ndi owuma
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