Mirabegron CAS:223673-61-8 Wopanga Wopanga Chithunzi Chodziwika

Mirabegron CAS:223673-61-8 Wogulitsa Wopanga

Mirabegron ndi yothandiza pochiza kufulumira, kuchuluka kwa mkodzo, komanso kusadziletsa kwa mkodzo komwe kumakhudzana ndi chikhodzodzo chogwira ntchito mopitirira muyeso (OAB). Mirabegron imapangidwa pophatikiza 4-nitrophenethyl amine ndi (R)-2-hydroxy-2-phenylacetic acid. Amide yomwe imatuluka imachepetsedwa kukhala amine. Gulu la nitro limachepetsedwa ndipo zotsatira zake zimagwirizanitsidwa ndi 2-(2-aminothiazol-4-yl) acetic acid kuti ipereke mirabegron.

Oda kapena Pemphani Mtengo

Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Kugwiritsa Ntchito ndi Zotsatira zake

Mirabegron ndi mankhwala oletsa β3-adrenoceptor omwe amagwira ntchito pakamwa omwe akupangidwa ndi Astellas Pharma pochiza chikhodzodzo chogwira ntchito mopitirira muyeso (OAB). Mankhwalawa ndi otsutsana ndi nanomolar EC50 motsutsana ndi mayeso a biochemical a β3-AR a anthu omwe ali ndi kusankha bwino kuposa ma b1- ndi β2-AR. Mirabegron ikuwonetsa njira yatsopano poyang'ana β3-AR kuti chikhodzodzo chipumule kuti chithandize kuthana ndi zizindikiro za OAB monga kuwonjezeka kwa mkodzo komanso pafupipafupi komanso kusadziletsa mwachangu. Komabe, mirabegron ndi choletsa cytochrome P450 2D6, ndipo izi zikubweretsa nkhawa yokhudza kuyanjana kwa mankhwala ndi mankhwala ndikugwiritsa ntchito nthawi imodzi ma substrates ena a cytochrome P450 2D6.

Chitsanzo cha Zamalonda

Kulongedza Zinthu:

Zina Zowonjezera:

Kapangidwe kake	C21H24N4O2S
Kuyesa	99%
Maonekedwe	Ufa woyera mpaka wotumbululuka wachikasu
Nambala ya CAS	223673-61-8
Kulongedza	25KG
Moyo wa Shelufu	zaka 2
Malo Osungirako	Sungani pamalo ozizira komanso ouma
Chitsimikizo	ISO.