Novobiocin sodium mchere CAS: 1476-53-5

Mu sayansi ya tizilombo toyambitsa matenda, mchere wa sodium wa novobiocin umagwiritsidwa ntchito m'mayeso osiyanasiyana ozindikira matenda, monga mayeso a novobiocin susceptibility test kuti asiyanitse pakati pa coagulase-positive ndi coagulase-negative staphylococci. Kuyesaku kumaphatikizapo kubaya kachilombo ka bakiteriya m'ma agar plates owonjezeredwa ndi novobiocin ndikuwona malo oletsa kukula mozungulira diski ya maantibayotiki. Coagulase-positive staphylococci, kuphatikizapo Staphylococcus aureus, nthawi zambiri amakana novobiocin, pomwe coagulase-negative staphylococci imakana. Kuphatikiza apo, novobiocin imagwiritsidwa ntchito m'malo ofufuzira kuti iphunzire za bacterial DNA gyrase inhibition, njira zotsutsana ndi maantibayotiki, komanso momwe mankhwala amagwirira ntchito. Imagwira ntchito ngati chida chamankhwala chofufuzira za physiology ya bakiteriya, majini, ndi matenda, zomwe zimathandiza kumvetsetsa njira zotsutsana ndi maantibayotiki komanso kupanga njira zatsopano zochiritsira. Kupatula kugwiritsidwa ntchito kwake mu sayansi ya tizilombo toyambitsa matenda ndi kafukufuku, novobiocin ili ndi ntchito zochepa zachipatala chifukwa cha poizoni wake komanso kupezeka kwa njira zina zotetezeka. Komabe, ikadali gawo lofunikira kwambiri pa ntchito za labotale kuti adziwe mabakiteriya komanso kuyesa kuopsa kwa maantibayotiki, kuthandizira kuzindikira molondola komanso kuchiza matenda opatsirana ndi mabakiteriya moyenera. Kusamalira, kusunga, ndi kutaya mchere wa novobiocin sodium ndikofunikira kuti zitsimikizire chitetezo cha labotale komanso kuteteza chilengedwe, motsatira ndondomeko zokhazikitsidwa ndi malangizo oyendetsera.