Orlistat CAS: 96829-58-2 Wopanga Wopanga

Orlistat ndi yochokera ku semisynthetic ya lipstatin, metabolite yomwe ili kutali ndi Streptomyces toxytricini.Tetrahydrolipstatin imagwira ntchito ngati inhibitor yamphamvu, yosasinthika ya pancreatic lipase.Mu vivo, imalepheretsa kuyamwa kwa triglycerides pomwe imalola kuyamwa kwamafuta acid.Tetrahydrolipstatin imagwiritsidwa ntchito kwambiri pochiza kunenepa kwambiri.Orlistat ili ndi mphamvu yoletsa kulemera kwanthawi yayitali yomwe imachepetsa ndikusunga kulemera ndikuletsa kuyambiranso.Kugwiritsa ntchito Orlistat kumatha kuchepetsa zomwe zimachitika chifukwa cha kulemera ndi matenda, kuphatikizapo hypercholesterolemia, matenda a shuga a mtundu wa 2, kulolerana kwa shuga, hyperinsulinemia, ndi matenda oopsa, ndipo zimatha kuchepetsa mafuta m'ziwalo.