Simvastatin CAS: 79902-63-9 Wopanga Wopanga

Simvastatin ndi semisynthetic, hydrophobic pang'ono, analogue ya lovastatin.Monga lovastatin, simvastatin ndi inhibitor yeniyeni ya HMG-CoA reductase ndipo imagwiritsidwa ntchito pochiza kuchepetsa LDL cholesterol.Posachedwapa, ma statins akhala ma probe ofunikira a biochemical mu cell biology.Kutenga nawo gawo muzochitika zambiri kumatha kulumikizidwa ndi machitidwe awo oyambira, komabe, machitidwe azinthu zina zambiri siziwoneka bwino. mevalonate, gawo loyambirira la cholesterol biosynthesis.Amagwiritsidwa ntchito pochiza hypercholesterolemia, chifukwa amachepetsa milingo ya otsika osalimba lipoproteins ndi triglycerides, ndikukweza kuchuluka kwa lipoprotein.