Sirolimus CAS:53123-88-9

Kuchepetsa Mphamvu ya Chitetezo cha Mthupi: Sirolimus imagwiritsidwa ntchito poletsa kukana ziwalo pambuyo poika impso. Nthawi zambiri imaperekedwa pamodzi ndi mankhwala ena oletsa chitetezo chamthupi kuti achepetse chiopsezo chokana ndikuwonjezera kupulumuka kwa graft. Coronary Stent Coating: Mu matenda a mtima, sirolimus imagwiritsidwa ntchito mu stent zoletsa mankhwala kuti apewe restenosis (kuchepetsanso) mitsempha yamagazi pambuyo pa angioplasty, kuthandiza kusunga patency ya mitsempha yamagazi ndikuchepetsa kufunikira kobwerezabwereza. Chithandizo cha Lymphangioleiomyomatosis (LAM): Sirolimus yavomerezedwa kuti ichite LAM, matenda osowa kwambiri a m'mapapo, kuti ipititse patsogolo ntchito ya mapapo ndikuchepetsa kupita patsogolo kwa matenda. Chithandizo cha Khansa: Imagwiritsidwa ntchito pochiza mitundu ina ya khansa, kuphatikiza khansa ya impso ndi amayi omwe asiya kusamba omwe ali ndi khansa ya m'mawere, zomwe zikuwonetsa zotsatira zotsutsana ndi kukula kwa khansa. Matenda a Khungu: Sirolimus yafufuzidwa kuti ingathe kuchiza matenda osiyanasiyana a khungu monga psoriasis, atopic dermatitis, ndi angiofibromas zokhudzana ndi tuberous sclerosis complex. Kuyika Mitsempha ya Mtima: Mu opaleshoni ya mitsempha yamagazi, kuyika kwa sirolimus-coated grafts kumagwiritsidwa ntchito poletsa hyperplasia ya intimal ndikulimbikitsa kukhala ndi nthawi yayitali yokonzanso mitsempha yamagazi. Njira Zofufuzira: Kafukufuku akuchitika pakugwiritsa ntchito sirolimus m'matenda odziteteza okha, monga systemic lupus erythematosus, komanso m'munda wa mankhwala obwezeretsa ndi uinjiniya wa minofu. Mwachidule, sirolimus imagwira ntchito yofunika kwambiri mu mankhwala osinthira ziwalo, matenda a mtima, khansa, ndi madera osiyanasiyana ochiritsira chifukwa cha mphamvu zake zoletsa chitetezo chamthupi komanso zoletsa kufalikira kwa maselo, zomwe zimathandiza kuti zotsatira za odwala zikhale bwino komanso kuti chithandizo chamankhwala chipitirire patsogolo.