Spironolactone CAS:52-01-7 Wopanga Wopanga

Spironolactone (Aldactone) ndi mankhwala omwe adapangidwa poyamba ngati mineralocorticoid antagonist ndipo amagwiritsidwa ntchito ngati diuretic ndi antihypertensive agent.Komabe, pamiyeso yayikulu spironolactone imamangiriza ku cholandilira cha androgen.Muzochita zachipatala ndi wotsutsa wofooka wa androgen wogwiritsidwa ntchito pochiza hirsutism mwa amayi mwa kutsekereza testosterone kumangiriza kwa androgen receptors mu follicles tsitsi.Kugwiritsa ntchito spironolactone mwa amayi pochiza hirsutism kapena dazi lachimuna kungayambitse kuchuluka kwa potaziyamu mu seramu;miyesoyi iyenera kufufuzidwa mkati mwa mwezi wa 1 kuyambira mankhwala.Spironolactone (Aldactone) imagwirizana mwadongosolo ndi aldosterone ndipo imakhala ngati inhibitor yopikisana pofuna kuteteza kumangidwa kwa aldosterone ku mapuloteni ake enieni omanga ma cell.