CAS ya tert-butyl (2-chloropyridin-3-yl)carbamate:209798-48-1

Tert-butyl (2-chloropyridin-3-yl)carbamate imagwira ntchito yofunika kwambiri ngati pakati pa kupanga mankhwala ovuta, opatsa thanzi omwe ali ndi ntchito zomwe zingatheke pa mankhwala. Kuphatikizidwa kwake mu mamolekyulu kumathandiza ofufuza kufufuza mankhwala atsopano omwe akuyang'ana madera ochiritsira monga matenda amitsempha, matenda opatsirana, kapena khansa. Kupezeka kwa gulu la chloropyridine kumapereka reactivity yeniyeni ndi katundu wa pharmacophoric, zomwe zimapangitsa kuti likhale lofunika pa kafukufuku wa chemistry yamankhwala. Pakupeza mankhwala, mankhwalawa angagwiritsidwe ntchito ngati poyambira popanga mankhwala omwe angakhale nawo, pogwiritsa ntchito mawonekedwe ake kuti asinthe ntchito ya zamoyo ndi katundu wa pharmacokinetic. Kuphatikiza apo, gulu la tert-butyl limapereka cholepheretsa cha steric, chomwe chimakhudza kuyanjana kwa mankhwala ndi zolinga zamoyo ndikuthandizira kufufuza mankhwala atsopano. Kuphatikiza apo, m'malo ophunzirira ndi mafakitale, ofufuza angagwiritse ntchito nyumbayi kukonzekera malaibulale amitundu yosiyanasiyana ya zinthu zomwe zimachokera ku kapangidwe kake ndi ntchito, zomwe zimathandiza kuzindikira mankhwala a lead omwe ali ndi zotsatira zomwe zimafunidwa pazamoyo. Udindo wake pakupanga mankhwala umafikira pakupanga mankhwala ophatikizana ndi kupanga njira zatsopano zopangira, kuwonetsa kufunika kwake kwakukulu m'magawo asayansi. Ponseponse, tert-butyl (2-chloropyridin-3-yl)carbamate imagwira ntchito yofunika kwambiri pakufunafuna njira zatsopano zopezera mankhwala ndi kafukufuku wa mankhwala, zomwe zimapangitsa kuti pakhale njira yopangira mamolekyu osiyanasiyana ogwira ntchito m'thupi komanso mankhwala ena.