4-Nitrophenyl Beta-D-glucuronide CAS:10344-94-2

4-Nitrophenyl Beta-D-glucuronide ndi mankhwala opangidwa ndi kulumikiza molekyulu ya shuga ku gulu la 4-nitrophenyl kudzera mu mgwirizano wa glycosidic.Nthawi zambiri amagwiritsidwa ntchito ngati gawo laling'ono muzitsulo za enzymatic kuti azindikire kukhalapo ndi ntchito za β-glucuronidase, enzyme yomwe imakhudzidwa ndi metabolism ya mankhwala osiyanasiyana ndi xenobiotics mu zinyama. ndi gulu la 4-nitrophenyl, zomwe zimapangitsa kuti 4-nitrophenol itulutsidwe, yomwe imatha kuzindikirika ndi spectrophotometrically pa 400-420 nm.Kuchita kwa enzymatic kumeneku kumapereka muyeso wochulukira wa zochitika za β-glucuronidase ndipo nthawi zambiri amagwiritsidwa ntchito ngati chida pofufuza mankhwala, maphunziro a toxicology, ndi matenda achipatala.

Konzani kapena Funsani Mtengo

Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Kugwiritsa Ntchito ndi Zotsatira

Kuzindikira ntchito ya β-glucuronidase: 4-NPBG imagwiritsidwa ntchito kwambiri ngati gawo la chromogenic kuti liwone kukhalapo ndi ntchito ya β-glucuronidase mu zitsanzo zosiyanasiyana zamoyo.Enzyme imadula mgwirizano wa glycosidic wa 4-NPBG, kupanga 4-nitrophenol, yomwe ingayesedwe pogwiritsa ntchito spectrophotometry.

Maphunziro a kagayidwe ka mankhwala: Popeza β-glucuronidase imagwira ntchito yofunika kwambiri pa metabolism ya mankhwala ndi xenobiotics, 4-NPBG ingagwiritsidwe ntchito kuyesa ntchito ya enzymeyi mu maphunziro a kagayidwe ka mankhwala.Imathandiza kumvetsetsa kukula ndi kinetics ya glucuronidation reaction, yomwe ndi yofunikira pakuvomerezeka kwa mankhwala ndi bioavailability.

Maphunziro a Toxicology: Zinthu zina za toxological zimatha kusinthidwa ndikutulutsidwa ngati glucuronide conjugates.Pogwiritsa ntchito 4-NPBG ngati gawo lapansi, ochita kafukufuku amatha kufufuza ntchito ya β-glucuronidase m'magulu osiyanasiyana kapena mizere ya maselo kuti awone zomwe zingakhale zoopsa kapena zotsatira za mankhwala.

Kuwunika kwachipatala: Kuyeza kwa ntchito ya β-glucuronidase pogwiritsa ntchito 4-NPBG kungagwiritsidwe ntchito pazochitika zachipatala kuti azindikire matenda kapena zochitika zina.Milingo yolakwika kapena zochita za β-glucuronidase zitha kuwonetsa zovuta zina za majini, kulephera kwa chiwindi, kapena khansa.

Product Chitsanzo

Kulongedza katundu:

Zina Zowonjezera:

Kupanga	C12H13NO9
Kuyesa	99%
Maonekedwe	White ufa
CAS No.	10344-94-2
Kulongedza	Zing'onozing'ono ndi zambiri
Shelf Life	zaka 2
Kusungirako	Sungani pamalo ozizira ndi owuma
Chitsimikizo	ISO.