Candesartan CAS: 139481-59-7 Wopanga Wopanga

Candesartan ndi wotsutsa wa angiotensin II receptor I (AT1), IC50s=1.12 ndi 2.86 nM wa bovine adrenal cortex ndi kalulu aorta motsatana. Mosankha amaletsa kutsika kwa angiotensin II-kuchititsa kukomoka kwa mikwingwirima ya kalulu popanda kusokoneza ndi kukomoka kwina , KCl, serotonin, PGF2αkapena endothelin.

Konzani kapena Funsani Mtengo

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Kugwiritsa Ntchito ndi Zotsatira

Candesartan ndi wosankha wa AT1 (angiotensin II receptor 1).Kutsutsana kwa angiotensin receptors kumalepheretsa vasoconstriction ndi kupanga aldosterone, zomwe zimapangitsa kuchepa kwa madzi ndi sodium m'madzi am'magazi.Imawonetsa zotsatira za antihypertensive mu zitsanzo za nyama.Amagwiritsidwa ntchito pochiza congestive mtima kulephera, monga antihypertensive.Candesartan sichimakhudza kukhalapo kwa maselo kapena kuchulukana koma kumawonjezera kufotokozera kwa VEGF ndi interleukin-8 mu sing'anga yotukuka ya ma cell a KU-19-19.Candesartan (0.1 nM) imatha kuchepetsa kuyankha kwamphamvu kwa angiostensin II ndi pafupifupi 50%.

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Kupanga	Chithunzi cha C24H20N6O3
Kuyesa	99%
Maonekedwe	White ufa
CAS No.	139481-59-7
Kulongedza	1KG 25KG
Shelf Life	zaka 2
Kusungirako	Sungani pamalo ozizira ndi owuma
Chitsimikizo	ISO.