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Lasmiditant CAS:439239-90-4
Lasmiditan, yomwe imagulitsidwa pansi pa dzina la Reyvow, ndi mankhwala atsopano omwe adapangidwa kuti achepetse kuukira kwa mutu waching'alang'ala mwa akuluakulu. Ili m'gulu la ma agonists osankhidwa a serotonin receptor, makamaka omwe amayang'ana kwambiri mtundu wa 5-HT1F receptor. Njira imeneyi yogwirira ntchito imasiyanitsa Lasmiditan ndi mankhwala achikhalidwe a mutu waching'alang'ala, chifukwa sichimayambitsa kutsekeka kwa mitsempha yamagazi, zomwe zimapangitsa kuti ikhale yoyenera kwa odwala omwe ali ndi chiopsezo cha matenda amtima.
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N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
N-Methylcarbonyl-2-chloroacetamidrazone ndi mankhwala odziwika bwino chifukwa cha ntchito zake zosiyanasiyana mu kapangidwe ka organic ndi chemistry yogwirizanitsa. Kupanga kwake kumaphatikizapo momwe N-methylcarbamoyl chloride imagwirira ntchito ndi 2-chloroacetohydrazide, zomwe zimapangitsa kuti pakhale mankhwala okhala ndi mawonekedwe osiyanasiyana komanso magwiridwe antchito. Mankhwalawa amadziwika ndi kuthekera kwake kupanga ma complexes ndi ma ayoni osiyanasiyana achitsulo, zomwe zimapangitsa kuti akhale ofunika kwambiri mu maphunziro a chemistry yogwirizanitsa. Kuphatikiza apo, magulu ake a carbonyl ndi amidrazone amathandizira ku reactivity yake komanso ntchito zomwe zingatheke za mankhwala, zomwe ndi madera omwe akupitilira kufufuza.
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Lasmiditan HCl CAS:613677-28-4
Lasmiditan hydrochloride (Lasmiditan HCl) ndi mankhwala omwe amadziwika ndi ntchito yake pochiza mutu waching'alang'ala mwa akuluakulu. Lasmiditan HCl, yomwe idapangidwa ngati agonist yosankha serotonin receptor, makamaka yolunjika ku 5-HT1F receptor subtype, imayimira kupita patsogolo kwakukulu pa chithandizo cha mutu waching'alang'ala chifukwa cha njira yake yapadera yogwirira ntchito komanso mphamvu yake yochizira matenda.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, yomwe imadziwikanso kuti aminopyridine methylpiperidone, ndi mankhwala omwe ali ndi tanthauzo lalikulu mu kafukufuku wa mankhwala ndi mankhwala. Popangidwa kudzera mu 6-aminopicolinic acid ndi 1-methylpiperidin-4-one, mankhwalawa ali ndi mawonekedwe apadera omwe amathandizira kuti mankhwala ake akhale ndi mphamvu komanso magwiridwe antchito osiyanasiyana.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-Quinuclidinol, yomwe imadziwikanso kuti quinuclidinol, ndi chinthu chofunikira kwambiri mu chemistry yachilengedwe ndi kafukufuku wamankhwala chifukwa cha kapangidwe kake komanso ntchito zake zosiyanasiyana. Chomera ichi cha chiral chimachokera ku quinuclidine ndipo chili ndi mphamvu zosiyana za mankhwala ndi mankhwala zomwe zakopa chidwi m'magawo osiyanasiyana asayansi.
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APREPITANT INTERMEDIATES CAS:171482-05-6
Mankhwala ophatikizana a Aprepitant amagwira ntchito yofunika kwambiri popanga mankhwala a aprepitant, mankhwala amphamvu a neurokinin-1 (NK1) omwe amagwiritsidwa ntchito makamaka popewa nseru ndi kusanza komwe kumabwera chifukwa cha mankhwala a chemotherapy (CINV). Mankhwala ophatikizana awa ndi ofunikira kwambiri panjira yopangira zinthu zambiri zomwe zimapangitsa kuti aprepitant apangidwe komaliza. Aprepitant yokha imadziwika chifukwa cha mphamvu yake yosamalira CINV, zomwe zimathandiza kwambiri odwala omwe akulandira mankhwala a chemotherapy. Kupanga aprepitant kumaphatikizapo masitepe angapo ofunikira, ndipo mankhwala ophatikizanawa amagwira ntchito ngati zomangira zomwe zimathandiza kupanga bwino mankhwala ofunikirawa.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
2,4,6-Trifluorobenzoyl chloride, yomwe imadziwikanso kuti trifluorobenzoyl chloride, ndi mankhwala ofunikira kwambiri omwe amagwiritsidwa ntchito kwambiri popanga zinthu zachilengedwe komanso m'mafakitale. Popangidwa kudzera mu chlorination ya 2,4,6-trifluorobenzoic acid, mankhwalawa ali ndi makhalidwe apadera omwe amathandizira kuti agwiritsidwe ntchito kwambiri m'magawo osiyanasiyana.
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4-Chloro-6-iodoquinazoline CAS:98556-31-1
4-Chloro-6-iodoquinazoline ndi mankhwala omwe ali ndi formula ya molekyulu C9H5ClIN2. Amadziwika ndi kupezeka kwa maatomu a chlorine ndi ayodini omwe amamangiriridwa ku kapangidwe ka mphete ya quinazoline. Mankhwalawa amagwiritsidwa ntchito makamaka mu kafukufuku wamankhwala ndi kapangidwe ka organic chifukwa cha momwe angagwiritsire ntchito popanga mankhwala atsopano ndi mamolekyu ena omwe amagwira ntchito m'thupi.
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(R)-3-Quinuclinol CAS:25333-42-0
(R)-3-Quinuclinol, yomwe imadziwikanso kuti quinuclidinol, ndi chinthu chofunikira kwambiri mu chemistry yachilengedwe ndi kafukufuku wamankhwala chifukwa cha kapangidwe kake komanso ntchito zake zosiyanasiyana. Chomera ichi cha chiral chimachokera ku quinuclidine ndipo chili ndi mphamvu zosiyana za mankhwala ndi mankhwala zomwe zakopa chidwi m'magawo osiyanasiyana asayansi.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
Chomerachi (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate ndi molekyulu yovuta yachilengedwe yokhala ndi mawonekedwe akeake komanso mankhwala. Ili m'gulu la mankhwala a morpholine, omwe nthawi zambiri amagwiritsidwa ntchito mu chemistry yamankhwala chifukwa cha ntchito zawo zosiyanasiyana zamoyo.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine ndi mankhwala omwe amadziwika kuti amagwiritsidwa ntchito mosiyanasiyana mu kapangidwe ka organic ndi mankhwala. Popangidwa kudzera mu reaction ya (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone yokhala ndi ammonia kapena amine, mankhwalawa ali ndi mawonekedwe apadera omwe amathandizira kusiyanasiyana kwa magwiridwe antchito ake komanso ntchito zomwe zingatheke pamankhwala.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine ndi mankhwala omwe amadziwika ndi ntchito zake zosiyanasiyana mu kapangidwe ka organic ndi mankhwala. Popangidwa kudzera mu reaction ya 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone yokhala ndi ammonia kapena amine, mankhwalawa ali ndi mawonekedwe apadera omwe amathandizira kuti ntchito zake zigwire ntchito mosiyanasiyana komanso kuti azitha kuchita zinthu zosiyanasiyana.
