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N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea CAS:796848-79-8
N-(2-Chloro-4-hydroxyphenyl)-N'-cyclopropyl-urea ndi mankhwala omwe ali ndi formula ya molekyulu C10H11ClN2O2. Ndi m'gulu la zinthu zochokera ku urea zomwe zasinthidwa ndi gulu la chloro-hydroxyphenyl ndi gulu la cyclopropyl. Mankhwalawa amadziwika chifukwa cha kapangidwe kake komanso momwe angagwiritsire ntchito maphunziro osiyanasiyana a mankhwala ndi zamoyo.
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1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester CAS:205448-65-3
1,4-Dihydro-7-methoxy-4-oxo-6-quinolinecarboxylic acid methyl ester ndi mankhwala omwe ali ndi formula ya molekyulu C12H11NO4. Ili m'gulu la mankhwala a quinoline ndipo imadziwika ndi gulu la methyl ester lomwe limalumikizidwa ku mphete ya quinoline, yokhala ndi methoxy substituent pamalo 7 ndi gulu la keto pamalo 4.
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AZD-9291 mesylate CAS:1421373-66-1
AZD-9291 mesylate ndi mankhwala omwe ali ndi formula ya molekyulu C28H33N7O4∙CH4O3S. Ili m'gulu la zoletsa za tyrosine kinase ndipo imagwiritsidwa ntchito makamaka pochiza khansa ya m'mapapo yopanda maselo ang'onoang'ono (NSCLC). Mankhwalawa amasankha ndikuletsa mitundu yosinthika ya epidermal growth factor receptor (EGFR), yomwe imapezeka kwambiri mu zotupa za NSCLC.
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5-Chloromethyl-2H-1,2,4-triazolin-3-one CAS:252742-72-6
5-Chloromethyl-2H-1,2,4-triazolin-3-one ndi mankhwala ofunikira kwambiri omwe amagwiritsidwa ntchito mosiyanasiyana mu chemistry yamankhwala ndi kafukufuku wa agrochemical. Ndi m'gulu la zinthu zochokera ku triazolinone, zomwe zimasiyanitsidwa ndi kapangidwe kake kapadera ka molekyulu komwe kamathandizira pa ntchito zake zamoyo komanso momwe angagwiritsire ntchito pochiza.
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5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE CAS:42518-98-9
5-Chlorothiophene-2-carbonyl chloride ndi mankhwala omwe ali m'gulu la thienylacyl chloride. Amadziwika ndi kapangidwe kake ka molekyulu komwe kali ndi mphete ya thiophene yomwe yasinthidwa ndi gulu la chloro pamalo a 5 ndi gulu la carbonyl chloride pamalo a 2. Mankhwalawa ndi ofunikira kwambiri pakupanga zinthu zachilengedwe chifukwa cha momwe amagwirira ntchito mosiyanasiyana komanso momwe angagwiritsire ntchito mu sayansi ya mankhwala ndi zinthu.
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5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone CAS:503615-03-0
5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone ndi mankhwala omwe amadziwika chifukwa cha kapangidwe kake kovuta ka mamolekyulu komanso ntchito zosiyanasiyana mu chemistry yamankhwala ndi kafukufuku wamankhwala. Mankhwalawa ndi a gulu la pyridinones ndipo amadziwika ndi kapangidwe kake kapadera ka magulu ogwira ntchito, omwe amapereka zinthu zinazake zofunika kwambiri pa ntchito zake zamoyo.
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4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester CAS:5909-24-0
4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester ndi mankhwala omwe amadziwika chifukwa cha ntchito yake yofunika kwambiri mu kafukufuku wa mankhwala ndi mankhwala. Pokhala m'gulu la zinthu zochokera ku pyrimidine, mankhwalawa ali ndi kapangidwe kapadera ka molekyulu kofunikira kwambiri pa ntchito zake zamoyo komanso ntchito zake zochizira.
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3-CHLORO-4-METHOXYBENZYLAMINE HYDROCHLORIDE CAS:41965-95-1
3-Chloro-4-Methoxybenzylamine Hydrochloride ndi mankhwala odziwika bwino omwe amadziwika bwino chifukwa cha ntchito zake mu chemistry yamankhwala komanso kafukufuku wamankhwala. Mankhwalawa ali mgulu la aromatic amines ndipo amadziwika ndi kapangidwe kake ka magulu ogwira ntchito ofunikira pa ntchito zake zamoyo.
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3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one CAS:545445-44-1
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one ndi mankhwala odziwika bwino chifukwa cha kapangidwe kake kovuta ka mamolekyulu komanso ntchito zosiyanasiyana mu mankhwala ndi kupanga mankhwala. Mankhwalawa ali m'gulu la dihydropyridinones ndipo amadziwika ndi kapangidwe kake kovuta ka magulu ogwira ntchito, omwe amapereka zinthu zinazake zofunika kwambiri pa ntchito zake zamoyo.
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L(-)-Thiazolidine-4-carboxylic acid CAS:34592-47-7
L(-)-Thiazolidine-4-carboxylic acid ndi mankhwala odziwika bwino omwe amadziwika chifukwa cha ntchito zake zosiyanasiyana mu chemistry yamankhwala komanso kafukufuku wamankhwala. Pokhala m'gulu la zinthu zochokera ku thiazolidine, mankhwalawa ali ndi kapangidwe kapadera ka mamolekyulu kofunikira kwambiri pa ntchito zake zamoyo komanso mphamvu zake zochizira.
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Nintendonib CAS:656247-17-5
Nintedanib ndi molekyulu yaying'ono yamphamvu yotchedwa tyrosine kinase inhibitor (TKI) yomwe imagwira ntchito yofunika kwambiri pochiza khansa ndi matenda a fibrotic. Imagwira ntchito yake yamankhwala polimbana ndi ma receptor ambiri a tyrosine kinases omwe amakhudzidwa ndi angiogenesis, fibrogenesis, ndi kukula kwa chotupa.
