Opanga ndi Ogulitsa Mankhwala Abwino - China Fakitale Yabwino Yamankhwala

Tetrabenzyl Dapagliflozin CAS:2001088-28-2

Tetrabenzyl dapagliflozin ndi mankhwala omwe ali ndi formula ya molekyulu C86H92O23S2 ndipo ali m'gulu la mankhwala ochokera ku dapagliflozin. Amadziwika ndi kapangidwe kake, komwe dapagliflozin imalowetsedwa m'malo ndi magulu anayi a benzyl. Mankhwalawa ndi ofunikira kwambiri pa kafukufuku wa mankhwala ndi mankhwala chifukwa cha kapangidwe kake kapadera komanso momwe angagwiritsire ntchito popanga mankhwala.

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(Z)-Methyl 2-ethoxy-3-((2′-(N'-hydroxycarbaMiMidoyl)biphenyl-4-yl)Methyl)-3H-benzo[d] iMidazole-4-carboxylate CAS:147403-65-4

(Z)-Methyl 2-ethoxy-3-((2′-(N'-hydroxycarbamidoyl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate imapangidwa kudzera mu machitidwe osiyanasiyana achilengedwe kuyambira pazinthu zoyambira zomwe zimapezeka m'masitolo. Kupanga kumaphatikizapo kupanga chimango cha benzoimidazole kutsatiridwa ndi kuyambitsa gulu la biphenylcarbamidoyl ndi magwiridwe antchito a ethoxy-carbonyl. Njira zopangira izi zimafuna kuwongolera kolondola pazochitika za reaction kuti zikwaniritse regioselectivity yabwino komanso phindu la chinthu chomaliza.

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(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydropyran-3,4,5-triyl Triacetate CAS:461432-25-7

(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydropyran-3,4,5-triyl Triacetate, yokhala ndi formula ya molekyulu C24H29ClO8, ndi mankhwala omwe amagawidwa m'magulu a tetrahydropyran. Ili ndi kapangidwe kovuta kophatikiza mphete ya tetrahydropyran yomwe imalowetsedwa m'malo ndi gulu la acetoxymethyl ndi mphete ya phenyl yokhala ndi chloro ndi 4-ethoxybenzyl substituents. Mankhwalawa ali ndi zinthu zodabwitsa zomwe zimapangitsa kuti ikhale yofunikira popanga zinthu zachilengedwe komanso mwina mu ntchito zamankhwala.

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5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID CAS:24065-33-6

5-Chlorothiophene-2-carboxylic Acid, yomwe nthawi zambiri imafupikitsidwa kuti imveke bwino, ndi mankhwala omwe amadziwika ndi kuuma kwake komanso kufunika kwake mu kapangidwe kake ka organic ndi mankhwala. Kuphatikiza pakati pa thiophene ndi gulu la carboxylic acid pamalo achiwiri, kumapereka mwayi wosintha kapangidwe kake mosiyanasiyana komanso kufufuza bwino zamoyo.

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Diethyl 1,3-acetonedicarboxylate CAS:105-50-0

Diethyl 1,3-acetonedicarboxylate ndi mankhwala omwe amagwiritsidwa ntchito popanga zinthu zachilengedwe komanso kafukufuku wa mankhwala. Ndi m'gulu la ma ester a acetonedicarboxylate, omwe amadziwika ndi kapangidwe kake ka diethyl ester. Mankhwalawa amapangidwa chifukwa cha ntchito yake yomanga yosinthasintha popanga mankhwala ndi mamolekyu ovuta achilengedwe.

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Strontium ranelate CAS:135459-87-9

Strontium ranelate ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda a osteoporosis. Amapangidwa ndi ma atomu awiri a strontium omangiriridwa ku molekyulu imodzi ya ranelic acid. Strontium ranelate imadziwika ndi ntchito zake ziwiri, zomwe zimathandiza kupanga mafupa pomwe zimaletsa kuyamwa kwa mafupa, motero zimathandiza kuwonjezera kuchuluka kwa mafupa ndikuchepetsa chiopsezo cha kusweka kwa mafupa.

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Tetraethyl ranelate CAS: 58194-26-6

Tetraethyl ranelate ndi mankhwala omwe amagwiritsidwa ntchito pofufuza zamankhwala. Ali m'gulu la zinthu zochokera ku ranelic acid ndipo amadziwika ndi kapangidwe kake ka tetraethyl. Mankhwalawa amapangidwa chifukwa cha ntchito zake zamankhwala, makamaka popanga mankhwala atsopano omwe amalunjika ku njira zinazake zamoyo kapena ma receptor.

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N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine CAS:1289942-66-0

N-[3-Fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine ndi mankhwala omwe amagwiritsidwa ntchito pofufuza zamankhwala. Ali m'gulu la amino acid ndipo amadziwika ndi magulu ake a fluoro, methylamino carbonyl, ndi alanine. Mankhwalawa amapangidwa chifukwa cha ntchito zake zamankhwala, makamaka popanga mankhwala okhudzana ndi njira zinazake zamoyo kapena ma receptor.

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Clevidipine CAS:166432-28-6

Clevidipine ndi mankhwala omwe amagwiritsidwa ntchito chifukwa cha mphamvu zake zochepetsera kuthamanga kwa magazi. Ili m'gulu la dihydropyridine calcium channel blockers ndipo imadziwika chifukwa cha kuyamba kwake mwachangu komanso kugwira ntchito kwakanthawi kochepa. Clevidipine imagwiritsidwa ntchito kudzera m'mitsempha kuti ichepetse kuthamanga kwa magazi m'malo ochitira opaleshoni kapena pakagwa mwadzidzidzi. Kugwira kwake ntchito kosankha pa minofu yosalala ya mitsempha kumapangitsa kuti ikhale njira yabwino kwambiri yothanirana ndi kuthamanga kwa magazi kwambiri.

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4-(2,3-Dichloro-phenyl)-2,6-dimethyl -1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester CAS:110962-94-2

4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester ndi mankhwala omwe amagwiritsidwa ntchito pofufuza zamankhwala. Ndi a gulu la zinthu zochokera ku pyridine ndipo amadziwika ndi magulu ake a phenyl ndi ester omwe amalowetsedwa m'malo mwake. Mankhwalawa amapangidwa chifukwa cha ntchito zake zamankhwala, makamaka popanga mankhwala atsopano omwe amayang'ana njira zinazake zamoyo kapena ma receptors.

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3-Ethoxy-4-methoxy benzonitrile CAS:60758-86-3

3-Ethoxy-4-methoxy benzonitrile ndi mankhwala omwe amagwiritsidwa ntchito popanga mankhwala achilengedwe komanso kafukufuku wamankhwala. Ali m'gulu la zinthu zochokera ku benzonitrile ndipo amadziwika ndi magulu ake ogwira ntchito a ethoxy ndi methoxy. Mankhwalawa amapangidwa chifukwa cha ntchito yake ngati pakati pa kupanga mankhwala ndi mamolekyu ena ovuta achilengedwe.

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3-Acetamidophthalic Anhydride CAS: 6296-53-3

3-Acetamidophthalic Anhydride ndi mankhwala omwe amagwiritsidwa ntchito popanga zinthu zachilengedwe komanso m'mafakitale. Ali m'gulu la zinthu zochokera ku phthalic anhydride ndipo amadziwika ndi gulu lake la acetamido. Mankhwalawa amapangidwa ngati chinthu chofunikira kwambiri popanga utoto, utoto, ndi mankhwala ena apadera.

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