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Lincomycin hydrochloride CAS: 859-18-7
Lincomycin hydrochloride ndi mchere wa lincomycin, mankhwala opha tizilombo toyambitsa matenda a lincosamide omwe amadziwika kuti amagwira ntchito bwino polimbana ndi matenda osiyanasiyana a Gram-positive bacteria. Lincomycin hydrochloride ili ndi mphamvu zofanana ndi lincomycin ndipo imagwiritsidwa ntchito kwambiri pazachipatala pochiza matenda a pakhungu ndi minofu yofewa, matenda a m'mimba, matenda a m'mapapo, komanso matenda a m'mafupa. Mankhwala ake monga mchere wa hydrochloride amawonjezera kusungunuka ndi kukhazikika, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito parenteral komanso pakamwa m'malo azachipatala.
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Kanamycin base CAS: 8063-07-8
Kanamycin base ndi mankhwala opha tizilombo toyambitsa matenda a aminoglycoside omwe amagwiritsidwa ntchito kwambiri mu kafukufuku wa labotale komanso m'machitidwe azachipatala polimbana ndi matenda a bakiteriya. Imagwira ntchito poletsa kupanga mapuloteni m'mabakiteriya, zomwe zimapangitsa kuti ikhale yothandiza polimbana ndi tizilombo toyambitsa matenda ta Gram-positive ndi Gram-negative. Kanamycin base ndi yothandiza kwambiri pochiza matenda omwe amayamba chifukwa cha mabakiteriya ambiri osagwiritsa ntchito mankhwala, zomwe zimapereka njira yamphamvu yothandizira matenda akuluakulu a bakiteriya.
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Marbofloxacin CAS:115550-35-1
Marbofloxacin ndi mankhwala opha tizilombo toyambitsa matenda a ziweto otchedwa fluoroquinolone omwe amadziwika kuti amagwira ntchito bwino polimbana ndi mabakiteriya osiyanasiyana a Gram-negative ndi Gram-positive m'zinyama. Ndi m'gulu la fluoroquinolone la m'badwo wachitatu ndipo amagwiritsidwa ntchito kwambiri mu mankhwala a ziweto pochiza matenda a bakiteriya m'zinyama zina, ziweto, ndi nkhuku. Marbofloxacin imagwira ntchito mwamphamvu poletsa ma enzymes a DNA gyrase ndi topoisomerase IV, ofunikira kwambiri pakubwerezabwereza kwa DNA ya bakiteriya ndi njira zolembera. Imapezeka m'mankhwala akumwa ndi jakisoni, zomwe zimapangitsa kuti ikhale yothandiza kwambiri pothana ndi matenda opuma, mkodzo, komanso khungu m'madokotala a ziweto.
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Kanamycin A Sulfate CAS:25389-94-0
Kanamycin A sulfate ndi mankhwala opha tizilombo toyambitsa matenda a aminoglycoside omwe amagwiritsidwa ntchito kwambiri mu kafukufuku wa labotale komanso m'malo azachipatala kuti athane ndi matenda a bakiteriya. Imagwira ntchito poletsa kupanga mapuloteni m'mabakiteriya, zomwe zimapangitsa kuti ikhale yothandiza polimbana ndi tizilombo tambiri ta Gram-positive ndi Gram-negative. Kanamycin A sulfate ndi yofunika kwambiri pochiza matenda omwe amayamba chifukwa cha mabakiteriya ambiri omwe sagonjetsedwa ndi mankhwala, zomwe zimapereka njira yabwino kwambiri yochizira matenda akuluakulu a bakiteriya.
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Levofloxacin hydrochloride CAS:177325-13-2
Levofloxacin hydrochloride ndi mchere wa hydrochloride wochokera ku levofloxacin, mankhwala opha tizilombo toyambitsa matenda a fluoroquinolone omwe amadziwika kuti amagwira ntchito yolimbana ndi matenda osiyanasiyana a bakiteriya. Levofloxacin hydrochloride imakhala ndi mphamvu yofanana ndi ya levofloxacin ndipo imagwiritsidwa ntchito kwambiri chifukwa cha mphamvu zake zopha mabakiteriya a Gram-positive ndi Gram-negative. Kupangidwa kwake ngati mchere wa hydrochloride kumawonjezera kusungunuka ndi kukhazikika m'madzi, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito pakamwa komanso m'mitsempha m'malo azachipatala.
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Levofloxacin CAS:100986-85-4
Levofloxacin ndi mankhwala opha tizilombo toyambitsa matenda omwe ali m'gulu la fluoroquinolone, omwe nthawi zambiri amaperekedwa pochiza matenda a bakiteriya. Amagwira ntchito mwamphamvu motsutsana ndi mabakiteriya osiyanasiyana a Gram-positive ndi Gram-negative mwa kuletsa ma enzymes a DNA gyrase ndi topoisomerase IV, ofunikira pakuberekana kwa mabakiteriya. Levofloxacin imapezeka m'njira zamlomo ndi m'mitsempha, zomwe zimapangitsa kuti ikhale yothandiza pochiza matenda osiyanasiyana a bakiteriya monga matenda a kupuma, matenda a mkodzo, matenda a pakhungu, ndi zina zambiri.
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Kanamycin acid sulfate CAS: 64013-70-3
Kanamycin acid sulfate ndi mankhwala opha tizilombo toyambitsa matenda a aminoglycoside omwe amagwiritsidwa ntchito kwambiri mu kafukufuku wa labotale ndi m'malo azachipatala pochiza matenda osiyanasiyana a bakiteriya. Amathandiza poletsa kupanga mapuloteni a bakiteriya, zomwe zimapangitsa kuti ikhale yothandiza polimbana ndi mabakiteriya osiyanasiyana a Gram-positive ndi Gram-negative. Kanamycin acid sulfate ndi yothandiza kwambiri polimbana ndi matenda omwe amayamba chifukwa cha mabakiteriya ambiri osagwiritsa ntchito mankhwala, zomwe zimapangitsa kuti ikhale njira yabwino kwambiri yothandizira matenda akuluakulu a bakiteriya.
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Kanamycin sulfate CAS: 70560-51-9
Kanamycin sulfate ndi mankhwala opha tizilombo toyambitsa matenda omwe amagwiritsidwa ntchito kwambiri pofufuza za chikhalidwe cha maselo ndi zamoyo zamaselo. Ndi a gulu la maantibayotiki a aminoglycoside ndipo amagwira ntchito poletsa kupanga mapuloteni a bakiteriya. Kanamycin sulfate ndi ufa woyera wa kristalo womwe umasungunuka m'madzi, zomwe zimapangitsa kuti zikhale zosavuta kukonzekera mayankho ogwiritsidwa ntchito poyesera. Ndi wokhazikika pansi pa nthawi yosungira bwino ndipo amagwiritsidwa ntchito kwambiri m'ma laboratories chifukwa cha mphamvu yake yolimbana ndi mabakiteriya a Gram-negative.
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Mecillinam CAS:32887-01-7
Mecillinam, yomwe imadziwikanso kuti pivmecillinam, ndi mankhwala opha tizilombo toyambitsa matenda a penicillin omwe amagwira ntchito makamaka motsutsana ndi mabakiteriya a Gram-negative. Ili m'gulu la maantibayotiki a amidinopenicillin ndipo imagwirizana ndi ampicillin. Mecillinam imadziwika ndi luso lake lothana ndi Enterobacteriaceae, kuphatikizapo mitundu ya Escherichia coli ndi Klebsiella. Imagwira ntchito yopha tizilombo toyambitsa matenda mwa kuletsa kupanga makoma a maselo a bakiteriya kudzera mu kulumikizana ndi mapuloteni omangirira penicillin. Mecillinam imapezeka m'mankhwala opangidwa pakamwa, zomwe zimapangitsa kuti ikhale yoyenera kuchiza matenda a mkodzo ndi matenda ena omwe amayamba chifukwa cha tizilombo toyambitsa matenda a Gram-negative.
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Isepamicin sulfate CAS: 67814-76-0
Isepamicin sulfate ndi mankhwala opha tizilombo toyambitsa matenda a aminoglycoside omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana a bakiteriya. Amawonetsa mphamvu yopha tizilombo toyambitsa matenda motsutsana ndi mabakiteriya osiyanasiyana a Gram-positive ndi Gram-negative mwa kuletsa kupanga mapuloteni. Isepamicin sulfate ndi yothandiza kwambiri motsutsana ndi mitundu yosiyanasiyana yosamva mankhwala, zomwe zimapangitsa kuti ikhale njira yabwino kwambiri yothandizira matenda oopsa. Mankhwala opha tizilombo amenewa nthawi zambiri amaperekedwa kudzera m'mitsempha m'malo azachipatala moyang'aniridwa ndi akatswiri azaumoyo.
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Ionomycin wopanda asidi CAS:56092-81-0
Ionomycin free acid ndi mankhwala a calcium ionophore omwe amagwiritsidwa ntchito kwambiri m'malo ofufuzira kuti aphunzire njira zolumikizirana ndi ma cell ndi calcium dynamics. Amathandizira kunyamula ma calcium ions kudutsa ma cell membranes, zomwe zimapangitsa kuti calcium yambiri ichuluke m'ma cell. Ionomycin free acid imagwiritsidwa ntchito kwambiri mu ma cell biology tests kuti ayambitse njira zodalira calcium, monga kupanga cytokine, apoptosis, ndi kuchulukana kwa maselo. Kutha kwake kuyambitsa mayankho enaake a maselo posintha kuchuluka kwa calcium m'ma cell kumapangitsa kuti ikhale chida chofunikira kwambiri pakufufuza kwasayansi kosiyanasiyana.
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Gentamycin Sulfate CAS:1405-41-0
Gentamicin sulfate ndi mankhwala opha tizilombo toyambitsa matenda omwe ali m'gulu la aminoglycoside, omwe amagwiritsidwa ntchito kwambiri pochiza matenda osiyanasiyana a bakiteriya. Amawonetsa mphamvu yamphamvu yopha tizilombo toyambitsa matenda motsutsana ndi mabakiteriya osiyanasiyana a Gram-negative ndi ena a Gram-positive mwa kusokoneza kapangidwe ka mapuloteni. Gentamicin sulfate imapezeka m'njira zosiyanasiyana, kuphatikizapo jakisoni ndi mankhwala opangidwa pakhungu, zomwe zimapangitsa kuti ikhale yothandiza pochiza matenda opatsirana m'thupi komanso m'malo ena.
