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Zogulitsa

Mirabegron CAS: 223673-61-8 Wopanga Wopanga

Mirabegron ndi yochizira mwachangu, pafupipafupi mkodzo, komanso kusakhazikika kwa mkodzo komwe kumalumikizidwa ndi chikhodzodzo chochuluka (OAB).Mirabegron imapangidwa pophatikiza 4-nitrophenethyl amine ku (R) -2-hydroxy-2-phenylacetic acid.Zotsatira za amide zimachepetsedwa kukhala amine.Gulu la nitro limachepetsedwa ndipo zotsatira zake zimaphatikizidwa ndi 2-(2-aminothiazol-4-yl) acetic acid kuti apereke mirabegron.


Tsatanetsatane wa Zamalonda

Zogulitsa Tags

Kugwiritsa Ntchito ndi Zotsatira

Mirabegron ndi β3-adrenoceptor agonist yogwira pakamwa yomwe ikupangidwa ndi Astellas Pharma pochiza chikhodzodzo chochuluka (OAB).Mankhwalawa ndi nanomolar EC50 antagonist motsutsana ndi anthu β3-AR biochemical assays ndi kusankha bwino pa b1- ndi β2-ARs.Mirabegron ikuwonetsa njira yatsopano poyang'ana β3-AR yopumula kwa chikhodzodzo kuti ithandizire kuwongolera zizindikiro za OAB monga kuchuluka kwachangu kwa mkodzo komanso pafupipafupi komanso kusadziletsa mwachangu.Komabe, mirabegron ndi cytochrome P450 2D6 inhibitor, ndipo imadzutsa kukhudzidwa kwa kugwirizana kwa mankhwala ndi mankhwala ndi makonzedwe ena a cytochrome P450 2D6.

Product Chitsanzo

Chithunzi cha 272(1)
Chithunzi cha 273(1)

Kulongedza katundu:

Chithunzi cha 210(1)

Zina Zowonjezera:

Kupanga Chithunzi cha C21H24N4O2S
Kuyesa 99%
Maonekedwe Ufa Woyera mpaka Pale Yellow
CAS No. 223673-61-8
Kulongedza 25KG
Shelf Life zaka 2
Kusungirako Sungani pamalo ozizira ndi owuma
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