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Venlafaxine CAS: 93413-69-5
Venlafaxine ndi antidepressant ya kalasi ya serotonin ndi norepinephrine reuptake inhibitor (SNRI).Mankhwalawa adapangidwa koyamba ndi Wyeth mu 19Chemicalbook93 ndipo tsopano akugulitsidwa ndi Pfizer.Mankhwalawa amavomerezedwa kuti athe kuchiza matenda aakulu ovutika maganizo (MDD), matenda ovutika maganizo (GAD), ndi kuvutika maganizo komwe kumakhudzana ndi nkhawa.
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β-Nicotinamide Mononucleotide CAS: 1094-61-7
Nicotinamide mononucleotide (NMN), chopangidwa ndi NAMPT reaction ndi NAD + yapakatikati, imathandizira kusalolera kwa shuga pobwezeretsa milingo ya NAD + mu mbewa za T2D zopangidwa ndi HFD.NMN imathandiziranso kukhudzidwa kwa insulin ya chiwindi ndikubwezeretsanso mawonekedwe a jini okhudzana ndi kupsinjika kwa okosijeni, kuyankha kotupa, ndi nyimbo ya circadian, pang'ono kudzera mu kuyambitsa kwa SIRT1.NMN imagwiritsidwa ntchito pophunzira zomangira zomangira mkati mwa ma aptamers a RNA ndi ma activation a ribozyme okhudzana ndi zidutswa za β-nicotinamide mononucleotide (β-NMN) -activated RNA.
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β-Nicotinamide Adenine Dinucleotide CAS:53-84-9
β-Nicotinamide adenine dinucleotide (NAD) ndi mawonekedwe a oxidized a β-Nicotinamide Adenine Dinucleotide.Imakhala ngati anion pansi pazikhalidwe za physio-logic.Imagwira ntchito ndi deamido-NAD zwitterion.Ndilo maziko a conjugate a NAD (+).Imapezeka kwambiri m'chilengedwe ndipo imakhudzidwa ndi machitidwe ambiri a enzymatic momwe imagwirira ntchito ngati chonyamulira ma elekitironi mwa kukhala alternately oxidized (NAD+) ndi kuchepetsedwa (NADH).
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β-Nicotinamide Adenine Dinucleotide, mawonekedwe ochepetsedwa CAS:606-68-8
β-Nicotinamide adenine dinucleotide (NAD +) ndi β-Nicotinamide adenine dinucleotide, yochepetsedwa (NADH) imakhala ndi coenzyme redox pair (NAD +: NADH) yomwe imakhudzidwa ndi machitidwe ambiri a enzyme catalyzed reduction reduction reactions.Kuphatikiza pa ntchito yake ya redox, NAD+/NADH ndiwopereka mayunitsi a ADP-ribose mu ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and precursor of cyclic ADP-ribose (ADP-ribosyl cyclases) .
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β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Salt, mawonekedwe ochepetsedwa CAS:2646-71-1
NADPH ndiye mawonekedwe ochepetsedwa a coenzyme NADP+;amagwiritsidwa ntchito muzochita za anabolic monga lipid ndi nucleic acid synthesis, zomwe zimafuna NADPH monga kuchepetsa wothandizira.NADPH, Tetrasodium Salt ndi A ubiquitous coenzyme yomwe imakhala ngati wopereka electron muzochita zambiri pogwiritsa ntchito dehydrogenase ndi reductase enzymes.Amapangidwa ndi kuchepetsedwa kwa cholandila ma elekitironi NADP +.Njira zotsatirazi zamoyo zikuphatikizapo NADPH: kupanga ma carbohydrate kuchokera ku CO2 panthawi ya photosynthesis, kusungirako kuchepa kwa glutathione mu erythrocytes, kuchepetsa thioredoxin.
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Thio-Nicotinamide Adenine Dinucleotide (Thio-NAD) CAS:4090-29-3
Thionicotinamide adenine dinucleotide ndi analogi wa NAD.Kugwiritsa ntchito Thio-NAD m'malo mwa NAD ngati gawo laling'ono la NAD (+) -owononga ma enzymes ndiwopindulitsa kwambiri popeza mawonekedwe ochepetsedwa a Thio-NAD amawonetsa kuwonjezeka kwakukulu kwa kuyamwa pa 405 nM, kutalika komwe kumapezeka kwambiri pa owerenga ma microplate.
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β-Nicotinamide Adenine Dinucleotide Phosphate Monosodium Salt CAS:1184-16-3
Nicotinamide adenine dinucleotide phosphate, yofupikitsidwa NADP+ kapena, m'mawu akale, TPN (triphosphopyridine nucleotide), ndi cofactor yomwe imagwiritsidwa ntchito muzochita za anabolic, monga Calvin cycle ndi lipid ndi nucleic acid syntheses, zomwe zimafuna NADPH ngati chochepetsera ('hydrogen source. ') Amagwiritsidwa ntchito ndi mitundu yonse ya moyo wama cell.
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Ciclopirox Ethanolamine CAS:41621-49-2 Wopanga Wopanga
Ciclopirox ethanolamine ndi antigfungal agent yotakata, imawonetsanso antibacterial zochita motsutsana ndi mabakiteriya ambiri a gram-positive ndi gram-negative, ndipo ali ndi anti-inflammatory properties.Amagwiritsidwa ntchito pochiza matenda a fungal pakhungu ndi msomali.
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Desvenlafaxine Succinate CAS:386750-22-7
Desvenlafaxine Succinate ndi serotonin yapawiri ndi norepinephrine reuptake inhibitor (SNRI) yomwe inavomerezedwa kuti ichiritse matenda aakulu ovutika maganizo (MDD) ku United States mu 2008. Pofuna kupititsa patsogolo mphamvu ndi chitetezo cha venlafaxine, Wyeth anapeza ndipo anapanga imodzi. Ma metabolites akuluakulu a venlafaxine, omwe ndi O-desmethyl metabolite (desvenlafaxine).
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Doxazosin Mesylate CAS: 77883-43-3 Wopanga Wopanga
Doxazosin mesylate ndi quinazoline pawiri kuti ndi kusankha inhibitor wa alpha1 subtype wa alpha adrenergic zolandilira.Doxazosin mesylate ndi mbadwo watsopano wa quinazolone α1 receptor blocker yopangidwa ndi kampani ya Pfizer (United States), Ili ndi theka la moyo wautali, ikuwonetsa zotsatira zake pakukulitsa mitsempha ya magazi, kuchepetsa kukana kwa mitsempha ndi kuchepetsa kuthamanga kwa magazi mwa kutsekereza ndi 1 receptor.Iwo akulimbikitsidwa kunja monga mzere woyamba mankhwala mankhwala odana ndi matenda oopsa ndi mankhwala a prostate matenda.
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L-Isoleucine CAS: 73-32-5 Wopanga Wopanga
L-Isoleucine, yomwe imadziwikanso kuti Isoleucine, ndi amino acid yomwe ndi isomer ya leucine.Ndikofunikira mu kaphatikizidwe ka hemoglobini ndikuwongolera shuga wamagazi ndi milingo yamphamvu.L-Isoleucine ndi isomer ya L-leucine ndipo ndi amino acid wofunikira.Amapangidwa kuchokera ku threonine ndipo ndi nthambi-chain hydrophobic amino acid.
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Captopril CAS: 62571-86-2 Wopanga Wopanga
Captopril ndiye amawerengedwa kwambiri mwa angiotensin-converting enzyme inhibitors omwe amaperekedwa ngati mankhwala a antihypertensive.Imatsekereza enzyme yotembenuza angiotensin, yomwe imalepheretsa mapangidwe a angiotensin II ndikuchepetsa mphamvu yake ya vasoconstricting pamitsempha yamagazi ndi venous.Kuthamanga kwapang'onopang'ono kwa mitsempha yam'mitsempha kumachepa, zomwe zimabweretsa kutsika kwa mitsempha yamagazi.
