Uridine,2′-deoxy-5-ethynyl- CAS:61135-33-9

5-ethynyl-2′-deoxyuridine (EdU) ndi analog ya nucleoside yomwe imagwiritsidwa ntchito kwambiri m'munda wa biology ya mamolekyulu ndi kafukufuku wa biology ya maselo. Nthawi zambiri imagwiritsidwa ntchito kulemba ndikupeza DNA yatsopano yopangidwa m'maselo amoyo kudzera mu njira yotchedwa "click chemistry." Njirayi imalola kuwona ndi kuwerengera kubwerezabwereza kwa DNA ndi kuchulukana kwa maselo. EdU yakhala njira yotchuka m'malo mwa thymidine analog bromodeoxyuridine (BrdU) chifukwa chogwirizana ndi fluorescence microscopy komanso kusowa kwa njira zovuta zochotsera DNA panthawi yozindikira. Kuphatikiza apo, kapangidwe ka mankhwala ka EdU kamalola kuzindikira kwapadera komanso kogwira mtima, zomwe zimapangitsa kuti ikhale chida chofunikira pophunzira kapangidwe ka DNA ndi kayendedwe ka maselo.

Oda kapena Pemphani Mtengo

Tsatanetsatane wa Zamalonda

Ma tag a Zamalonda

Kugwiritsa Ntchito ndi Zotsatira zake

Kuyesa Kuchuluka kwa Maselo: EdU ikhoza kuphatikizidwa mu DNA yobwerezabwereza panthawi ya gawo la S la kuzungulira kwa maselo. Izi zimapangitsa kuti ikhale chida chofunikira pophunzira kuchuluka kwa maselo ndi kapangidwe ka DNA.

Click Chemistry: EdU nthawi zambiri imagwiritsidwa ntchito limodzi ndi click chemistry, njira yosankha komanso yothandiza kwambiri yomwe imagwiritsidwa ntchito kuzindikira ma biomolecule. Njirayi imalola kuzindikira DNA yolembedwa ndi EdU m'maselo ndi minofu.

Kujambula kwa Microscopy ya Fluorescence: Kuphatikizidwa kwa EdU kumalola kuwona kapangidwe ka DNA pogwiritsa ntchito maikulosikopu ya fluorescence. Njirayi imapereka chida chofunikira pophunzira kugawikana kwa maselo ndi kuchulukana kwawo.

Kulongedza Zinthu:

Zina Zowonjezera:

Kapangidwe kake	C11H12N2O5
Kuyesa	99%
Maonekedwe	Ufa woyera
Nambala ya CAS	61135-33-9
Kulongedza	Kakang'ono komanso kochuluka
Moyo wa Shelufu	zaka 2
Malo Osungirako	Sungani pamalo ozizira komanso ouma
Chitsimikizo	ISO.