1,2,3,4,6-Penta-O-acetyl-D-mannopyranose CAS:25941-03-1

1,2,3,4,6-Penta-O-acetyl-D-mannopyranose imagwiritsidwa ntchito makamaka ngati kalambulabwalo mu kaphatikizidwe ka Glycosylated mankhwala.Glycosylation imatanthawuza njira yophatikizira molekyulu ya shuga, monga mannose, ku molekyulu ina (mwachitsanzo, mapuloteni, ma peptides, mankhwala) kuti asinthe katundu wawo kapena kupititsa patsogolo ntchito zawo.Mtundu wa acetylated wa D-mannose ungagwiritsidwe ntchito poyambitsa magulu a mannose m'mamolekyu osiyanasiyana kudzera muzochita za mankhwala.

Chimodzi mwazinthu zofunikira kwambiri za 1,2,3,4,6-Penta-O-acetyl-D-mannopyranose ndikuphatikiza katemera wa glycoconjugate.Polumikiza mannose acetylated ndi puloteni yonyamula, glycoconjugate imatsanzira kapangidwe ka ma antigen amtundu wina.Izi zimathandiza kulimbikitsa chitetezo chamthupi, zomwe zimapangitsa kupanga ma antibodies motsutsana ndi tizilombo toyambitsa matenda.

Kuphatikiza apo, mankhwalawa angagwiritsidwenso ntchito popanga ma glycosides ndi oligosaccharides, omwe amatha kugwiritsidwa ntchito ngati othandizira, ma enzyme inhibitors, ndi machitidwe operekera mankhwala.Pogwiritsa ntchito magulu a acetyl pa molekyu ya mannose, ofufuza amatha kusintha zinthu ndi machitidwe a mankhwalawa, kuwapangitsa kukhala osankha komanso ogwira mtima.