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3,3-Dimethyl-1-Butyne CAS:917-92-0
3,3-Dimethyl-1-butyne ndi mankhwala odziwika bwino chifukwa cha kapangidwe kake ka ma triple bond ndi magulu awiri a methyl omwe amamangiriridwa ku maatomu a carbon a triple bond. Amatchedwa tetramethylethyne ndipo amagwiritsidwa ntchito m'njira zosiyanasiyana zopangira mankhwala.
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6-Chloro-3-methyluracil CAS:4318-56-3
6-Chloro-3-methyluracil ndi yochokera ku uracil, maziko a pyrimidine, yokhala ndi magulu a chlorine ndi methyl omangiriridwa pamalo enaake pa mphete ya uracil. Kusintha kumeneku kumapatsa mankhwala ndi zamoyo zomwe zimakhalapo, zomwe zimapangitsa kuti zikhale zofunikira kwambiri pa kafukufuku wa zamankhwala ndi zamankhwala. Kapangidwe ka 6-Chloro-3-methyluracil kamakhudza momwe imagwirira ntchito mkati mwa machitidwe a zamoyo, makamaka pakupanga nucleic acid ndi kuletsa ma enzyme, zomwe ndizofunikira kwambiri pakupanga mankhwala ndi chitukuko cha mankhwala.
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4-Isothiocyanato-2-(trifluoromethyl)benzonitrile CAS:143782-23-4
4-Isothiocyanato-2- (trifluoromethyl)benzonitrile ndi mankhwala omwe amadziwika ndi gulu logwira ntchito la isothiocyanate lomwe limalumikizidwa ku mphete ya benzene yosinthidwa ndi trifluoromethyl. Imagwiritsidwa ntchito makamaka ngati chomangira chosiyanasiyana mu kapangidwe ka organic, zomwe zimathandiza kupanga mapangidwe ovuta a mamolekyulu ndi zinthu zogwirira ntchito.
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![Kutuluka(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyeste CAS:171489-59-1](https://cdn.globalso.com/xindaobiotech/5EVBWZZXL9LE4FA@55921.png)
Kutuluka(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyeste CAS:171489-59-1
(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester, chidule chake chomveka bwino, ndi mankhwala odziwika bwino chifukwa cha kapangidwe kake kovuta ka mamolekyulu komanso momwe angagwiritsire ntchito mankhwala. Mankhwalawa amaphatikiza pakati pa pyridoindole ndi mphete ya tetrahydrofuran yolumikizidwa ku gulu la chloroacetyl ndi gawo la 1,3-benzodioxol-5-yl, lomwe lili ndi magwiridwe antchito a methyl ester. Zinthu izi zimapangitsa kuti pakhale kusintha kwa kapangidwe kake komanso kufufuza bwino zamoyo.
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Candesartan ester wapakati C3 CAS:136285-65-9
Candesartan ester intermediate C3 ndi chinthu chofunikira kwambiri popanga Candesartan cilexetil, mankhwala odziwika bwino a angiotensin II receptor antagonist omwe amagwiritsidwa ntchito makamaka pochiza kuthamanga kwa magazi ndi kulephera kwa mtima. Mankhwalawa amagwira ntchito yofunika kwambiri mumakampani opanga mankhwala chifukwa cha udindo wake monga wotsogolera popanga Candesartan cilexetil bwino.
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Linagliptin interMediate F CAS:853029-57-9
Linagliptin Intermediate F ndi mankhwala ofunikira kwambiri popanga linagliptin, mankhwala amphamvu a dipeptidyl peptidase-4 (DPP-4) omwe amagwiritsidwa ntchito pochiza matenda a shuga amtundu wa 2. Mankhwalawa amagwira ntchito yofunika kwambiri mumakampani opanga mankhwala chifukwa cha kapangidwe kake ka mankhwala ndi magwiridwe antchito ake. Linagliptin, yomwe imadziwika kuti (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-(2,4,5-trifluorophenyl)-1,2-dihydroquinazolin-2(3H)-one, imagwira ntchito yake yochiritsa poletsa ntchito ya enzyme ya DPP-4, motero imawonjezera kuchuluka kwa mahomoni a incretin monga GLP-1 (glucagon-like peptide-1). Izi zimapangitsa kuti odwala omwe ali ndi matenda a shuga azilamulira bwino glycemic control.
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Candesartan Cilexetil Impurity 8 CAS:139481-28-0
Candesartan Cilexetil Impurity 8 ndi chinthu china chomwe chimapezeka panthawi yopangira Candesartan cilexetil, mankhwala oletsa angiotensin II omwe amagwiritsidwa ntchito makamaka pochiza kuthamanga kwa magazi ndi kulephera kwa mtima. Ngakhale kuti sakufunidwa mu mankhwala omaliza, kumvetsetsa ndi kuwongolera ma profiles a zonyansa ndikofunikira kwambiri kuti zitsimikizire kuti mankhwalawo ndi otetezeka, ogwira ntchito bwino, komanso kutsatira malamulo.
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![BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG299.png)
BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3
BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER ndi mankhwala odziwika bwino chifukwa cha kapangidwe kake kovuta ka mamolekyulu komanso momwe amagwiritsidwira ntchito pochiza matenda. Mankhwalawa amaphatikiza pakati pa benzoic acid ndi carbamate moiety yokhala ndi gulu la dimethylethoxy ndi ntchito ya nitro-methyl ester, zomwe zimapangitsa kuti ikhale yofunika kwambiri mu chemistry yamankhwala komanso kafukufuku wa biochemical chifukwa cha kapangidwe kake kapadera komanso ntchito zake zamoyo.
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pyridine-3-sulfonyl chloride CAS:16133-25-8
Pyridine-3-sulfonyl chloride ndi mankhwala odziwika bwino chifukwa cha ntchito zake zosiyanasiyana mu kupanga zinthu zachilengedwe komanso kafukufuku wamankhwala. Mankhwalawa, omwe amatchedwanso picolinoyl chloride, ali ndi pyridine core yomwe imalowetsedwa m'malo ndi gulu la sulfonyl chloride pamalo atatu, zomwe zimapangitsa kuti ikhale yofunika kwambiri chifukwa cha momwe imagwirira ntchito komanso momwe ingagwiritsire ntchito bwino mankhwala osiyanasiyana.
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5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile CAS:1240948-77-9
5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile ndi mankhwala omwe amadziwika ndi kapangidwe kake ka mamolekyu ndi momwe angagwiritsire ntchito mankhwala ndi kapangidwe ka organic. Mankhwalawa ali ndi pyrrole core yomwe imalowetsedwa m'malo mwa gulu la fluorophenyl ndi gulu la cyano pamalo enaake, zomwe zimapangitsa kuti ikhale yofunika kwambiri chifukwa cha kapangidwe kake komanso zochita zake zamoyo.
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Vonoprazan CAS:881681-00-1
Vonoprazan ndi mankhwala omwe amadziwika kuti ndi amphamvu chifukwa cha mphamvu zake zoletsa asidi m'mimba, zomwe zimawasiyanitsa ndi mankhwala oletsa ma proton pump (PPIs) chifukwa cha njira yake yapadera yogwirira ntchito. Mankhwalawa amaletsa H+, K+-ATPase proton pump m'maselo a m'mimba mwa maselo okhala ndi mphamvu zambiri komanso zogwira mtima, zomwe zimapangitsa kuti asidi asamayende bwino komanso nthawi zonse.
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N-(4-CYANO-PHENYL)-GLYCINE CAS:42288-26-6
N-(4-Cyano-phenyl)-glycine ndi mankhwala omwe amadziwika ndi kapangidwe kake ka mamolekyulu ndi momwe angagwiritsire ntchito m'magawo osiyanasiyana, makamaka mu chemistry yamankhwala ndi kafukufuku wa biochemical. Mankhwalawa amaphatikiza gulu la phenyl ndi gawo la glycine, zomwe zimapangitsa kuti likhale lofunika chifukwa cha kapangidwe kake komanso ntchito zake zamoyo.
