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N-Acetyl-L-cysteine CAS:616-91-1
N-Acetyl-L-cysteine (NAC) ndi mtundu wosinthidwa wa amino acid cysteine. Umapereka gwero la cysteine ndipo ukhoza kusinthidwa mosavuta kukhala tripeptide glutathione, antioxidant wamphamvu m'thupi. NAC imadziwika ndi mphamvu zake zotsutsana ndi ma antioxidants komanso mucolytic, zomwe zimapangitsa kuti ikhale yothandiza pa ntchito zosiyanasiyana zaumoyo.
Monga antioxidant, NAC imathandiza kuteteza maselo ku kuwonongeka komwe kumachitika chifukwa cha ma free radicals, mitundu ya okosijeni yogwira ntchito, ndi poizoni. Imathandizanso kupanga glutathione, komwe kumachita gawo lofunikira kwambiri pakuchotsa poizoni m'thupi komanso kusunga chitetezo chamthupi chathanzi.
NAC yaphunziridwa kuti ingathandize pa thanzi la kupuma, makamaka kwa anthu omwe ali ndi matenda monga matenda a bronchitis, COPD, ndi cystic fibrosis. Nthawi zambiri imagwiritsidwa ntchito ngati mankhwala ochotsera mafinya kuti athandize kuchepetsa ndi kumasula mafinya, zomwe zimapangitsa kuti zikhale zosavuta kuchotsa mpweya m'mapapo.
Kuphatikiza apo, NAC yawonetsa lonjezo lothandiza thanzi la chiwindi mwa kuthandiza kuchotsa zinthu zoopsa, monga acetaminophen, mankhwala ochepetsa ululu. Ikhozanso kuteteza chiwindi ku kuwonongeka komwe kumachitika chifukwa cha kumwa mowa.
Kuwonjezera pa mphamvu zake zoteteza ku ma antioxidants ndi kupuma, NAC yafufuzidwa kuti ipeze ubwino wake pa thanzi la maganizo. Kafukufuku wina akusonyeza kuti ikhoza kukhala ndi zotsatira zabwino pa matenda a maganizo, monga kuvutika maganizo ndi matenda okakamiza (OCD).
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GLYCYL-L-PROLINE CAS: 704-15-4
Glycyl-L-proline, yomwe imadziwikanso kuti glycylproline kapena Gym-Pro, ndi amino acid yomwe imapangidwa ndi amino acid glycine yomwe imalumikizidwa ndi amino acid L-proline. Ndi mankhwala omwe amapezeka mwachilengedwe omwe amapezeka mu collagen, puloteni yomwe imayang'anira kapangidwe ndi mphamvu za minofu yosiyanasiyana m'thupi. Glycyl-L-proline yaphunziridwa chifukwa cha ubwino wake wathanzi, kuphatikizapo kulimbikitsa thanzi la khungu, kuchepetsa kutupa, komanso kuthandizira thanzi la mafupa ndi mafupa. Imagwiritsidwanso ntchito popanga zodzikongoletsera chifukwa cha mphamvu zake zopatsa thanzi komanso zoteteza ku ma antioxidants.
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Guanidine Hydrochloride CAS:50-01-1
Guanidine hydrochloride ndi mankhwala omwe ali ndi formula ya molekyulu ya CH5N3·HCl. Ndi mankhwala amphamvu a chaotropic omwe amagwiritsidwa ntchito kwambiri mu biochemistry ndi molecular biology.
Guanidine hydrochloride nthawi zambiri imagwiritsidwa ntchito kuwononga mapuloteni, kusokoneza kapangidwe ka mapuloteni, ndi kufalitsa mapuloteni kuti ayeretsedwe. Ndi yothandiza kwambiri pakuswa ma hydrogen bonds ndikusokoneza kuyanjana kosalumikizana mkati mwa mapuloteni. Izi zimapangitsa kuti ikhale yothandiza pakusungunula mapuloteni omwe nthawi zambiri sasungunuka kapena amakhala osakanikirana.
Imagwiritsidwanso ntchito ngati cholimbitsa mapuloteni, kuteteza mapuloteni ku kusakanizika kosafunikira kapena kusokonekera kwachilengedwe panthawi yoyesera yosiyanasiyana ya biochemical ndi biophysical. Guanidine hydrochloride ingathandize kusunga kapangidwe kake ndi ntchito ya mapuloteni pansi pa mikhalidwe yosinthika..
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Acetylthiocholine iodide CAS:1866-15-5
Acetylthiocholine iodide ndi mankhwala omwe amagwiritsidwa ntchito kwambiri ngati gawo la mankhwala mu mayeso a enzyme kuti ayesere ntchito ya enzyme acetylcholinesterase (AChE). AChE ndi enzyme yomwe imathira hydrolyzes neurotransmitter acetylcholine, gawo lofunika kwambiri pothetsa kutumiza kwa chizindikiro pakati pa maselo a mitsempha.
Pamene acetylthiocholine iodide ikugwiritsidwa ntchito ndi AChE, gulu la acetyl limachotsedwa, zomwe zimapangitsa kuti ma ayoni a thiocholine ndi acetate apangidwe. Thiocholine imachitapo kanthu ndi reagent yopanda mtundu yotchedwa DTNB (5,5′-dithiobis (2-nitrobenzoic acid)) kuti ipange mankhwala achikasu otchedwa 5-thio-2-nitrobenzoate, omwe amatha kuyezedwa ndi spectrophotometric. Kuchuluka kwa kukula kwa mtundu kumayenderana mwachindunji ndi ntchito ya AChE mu chitsanzo.
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2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride mchere wawiri (21) CAS:67801-08-5
2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride double salt ndi crystalline compound yolimba yomwe imagwiritsidwa ntchito ngati reagent mu organic synthesis. Imakhala ndi diazonium cation, chloride anions, ndi zinc cations. Compound iyi imapereka kukhazikika komanso kusungunuka bwino, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito m'mankhwala osiyanasiyana komanso mankhwala.
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4,5-Diazafluoren-9-one CAS:50890-67-0
4,5-Diazafluoren-9-one ndi mankhwala omwe ali m'gulu la mankhwala a heterocyclic aromatic. Amapangidwa ndi mafupa a fluorene okhala ndi ma atomu awiri a nayitrogeni (diaza) ndi atomu ya okosijeni (imodzi) yolumikizidwa pamalo enaake. Amagwiritsidwa ntchito kwambiri ngati chomangira kapena pakati pa kapangidwe ka organic, makamaka pokonzekera mankhwala osiyanasiyana a organic, mankhwala, ndi utoto. Kapangidwe kake ndi reactivity yake zimapangitsa kuti ikhale chida chamtengo wapatali popanga mapangidwe osiyanasiyana a mamolekyulu ndi magulu ogwira ntchito.
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Tapso Sodium CAS: 105140-25-8 Mtengo wa Wopanga
3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid,Inesa zwitterionic buffering agent mu mawonekedwe a sodium salt. Amagwiritsidwa ntchito kwambiri muzoyesera za biochemical ndi molecular biology kuti asunge pH yokhazikika mu mayankho.It Imasungunuka kwambiri m'madzi ndipo ili ndi pKa yofanana ndi pH ya thupi, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito m'njira zosiyanasiyana monga kuyeretsa mapuloteni, kuyesa ma enzyme, kupanga maselo, ndi electrophoresis. Kapangidwe kake ka mankhwala komanso kugwirizana kwake ndi machitidwe a zamoyo zimapangitsa kuti ikhale gawo lofunikira kwambiri m'mapuloteni osiyanasiyana a labotale.
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4-Nitrophenyl phosphate di(tris) mchere CAS:68189-42-4
Mchere wa 4-Nitrophenyl phosphate di(tris) ndi mankhwala omwe amagwiritsidwa ntchito pofufuza ndi kuzindikira matenda a biochemical. Umagwiritsidwa ntchito kwambiri ngati gawo la mayeso a alkaline phosphatase enzyme. Mcherewu, ukaphikidwa ndi alkaline phosphatase, umapanga chinthu chachikasu chomwe chingayesedwe mosavuta ndi spectrophotometric. Izi zimagwiritsidwa ntchito kwambiri m'njira zosiyanasiyana, kuphatikizapo mayeso a enzyme-linked immunosorbent assays (ELISAs) ndi kuzindikira zochitika za phosphatase. Mphamvu ya mtundu wachikasu imagwirizana mwachindunji ndi ntchito ya enzyme, zomwe zimathandiza kuti kuchuluka kwa alkaline phosphatase kuwerengedwe molondola m'zitsanzo zamoyo. Mchere wa 4-Nitrophenyl phosphate di(tris) ndi wokhazikika, wosungunuka m'madzi, komanso wovuta kwambiri, zomwe zimapangitsa kuti ukhale chisankho chodziwika bwino cha mayeso a enzyme mu kafukufuku wa zamoyo ndi zamankhwala.
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Nitrotetrazolium blue chloride CAS:298-83-9
Nitrotetrazolium blue chloride, yomwe imadziwikanso kuti NBT kapena NBT-Cl, ndi mankhwala omwe amagwiritsidwa ntchito kwambiri poyesa zamoyo ndi zamankhwala. Ndi ufa wachikasu wopepuka womwe umasungunuka m'madzi.
NBT imagwiritsidwa ntchito nthawi zambiri ngati chizindikiro chodziwira kupezeka kwa ma superoxide radicals kapena ma enzyme omwe amawapanga. Imasintha mtundu ikachepetsedwa ndi ma superoxide radicals, kusintha kuchoka pachikasu kupita ku formazan precipitate yabuluu. Izi nthawi zambiri zimagwiritsidwa ntchito poyesa kuphunzira za kupsinjika kwa okosijeni, kupuma kwa maselo, ndi ntchito ya ma enzyme.
NBT imagwiritsidwa ntchito kwambiri m'njira zosiyanasiyana, monga kuchepetsa nitroblue tetrazolium, kuti iwonetse kupanga kwa superoxide m'maselo ndi minofu. Yagwiritsidwanso ntchito mu immunohistochemistry ndi histochemistry kuti ipeze ndikuzindikira ma enzyme ena ndi zigawo zina za maselo.
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NSP-AS CAS:211106-69-3 Mtengo wa Wopanga
Mchere wamkati wa 3-[9-(((3-(carboxypropyl)[4-Methxylphenyl]sulfonyl)aMine)carboxyl]-10-acridiniuMyl)-1-propanesulfonate ndi molekyulu yovuta yokhala ndi gawo la acridinium lolumikizidwa ku mchere wamkati wa propanesulfonate. Uli ndi gulu la carboxypropyl, gulu la 4-Methxylphenylsulfonyl, ndi gulu la amine. Mchere uwu mwina umapangidwa kuti ugwiritsidwe ntchito m'malo ena monga chemistry, mankhwala, kapena kafukufuku.
Kuphatikiza apo, NAC yawonetsa lonjezo lothandiza thanzi la chiwindi mwa kuthandiza kuchotsa zinthu zoopsa, monga acetaminophen, mankhwala ochepetsa ululu. Ikhozanso kuteteza chiwindi ku kuwonongeka komwe kumachitika chifukwa cha kumwa mowa.
Kuwonjezera pa mphamvu zake zoteteza ku ma antioxidants ndi kupuma, NAC yafufuzidwa kuti ipeze ubwino wake pa thanzi la maganizo. Kafukufuku wina akusonyeza kuti ikhoza kukhala ndi zotsatira zabwino pa matenda a maganizo, monga kuvutika maganizo ndi matenda okakamiza (OCD).
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L-Leucine p-nitroanilide hydrochloride CAS:16010-98-3
L-Leucine p-nitroanilide hydrochloride ndi mankhwala omwe ali m'gulu la zinthu zochokera ku p-nitroanilide. Ndi ufa wa kristalo woyera mpaka woyera womwe umagwiritsidwa ntchito kwambiri pofufuza za biochemical ndi kuyesa ma enzyme.
L-Leucine p-nitroanilide hydrochloride nthawi zambiri imagwiritsidwa ntchito ngati gawo loyezera ntchito ya ma enzyme monga ma protease ndi ma peptidases. Pamene ma enzyme amenewa amagawanika L-Leucine p-nitroanilide hydrochloride, imatulutsa p-nitroaniline, yomwe imatha kuzindikirika ndi spectrophotometric. Kuchuluka kwa kusintha kwa mtundu kumafanana mwachindunji ndi ntchito ya enzymatic, zomwe zimapangitsa kuti kuchuluka kwa ntchito ya enzyme kuwerengedwe m'zitsanzo zamoyo.
Mankhwalawa amasungunuka m'madzi ndipo amatha kusungunuka mosavuta m'njira zoyenera zogwiritsira ntchito poyesa ma enzyme. Ndikofunikira kusunga L-Leucine p-nitroanilide hydrochloride pamalo ozizira komanso ouma kuti ikhale yolimba.
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Guanidine Thiocyanate Sulfate CAS:593-84-0
Guanidine thiocyanate sulfate ndi mankhwala ochokera ku ma ayoni a guanidine, thiocyanate, ndi sulfate. Amagwiritsidwa ntchito kwambiri mu kafukufuku wa sayansi ya zamoyo ndi biochemistry ngati chaotropic.
Guanidine thiocyanate sulfate nthawi zambiri imagwiritsidwa ntchito mu njira zolekanitsira DNA ndi RNA kuti isokoneze ma cell membranes ndi mapuloteni owonongeka, zomwe zimathandiza kuti ma nucleic acids atulutsidwe bwino. Zimathandiza kuti DNA ndi RNA zisungunuke, zomwe zimathandiza kuti zilekanitsidwe ndi kuyeretsedwa kuchokera ku zitsanzo zosiyanasiyana zamoyo.
Chifukwa cha mphamvu zake za chaotropic, guanidine thiocyanate sulfate imathandiza kuswa mgwirizano wa hydrogen ndi kuyanjana kwina kosagwirizana ndi covalent, zomwe zimathandiza kulekanitsa ma nucleic acids ndi mapuloteni, lipids, ndi zigawo zina za ma cell. Zimathandizanso kuletsa ntchito ya RNase, kuonetsetsa kuti ma nucleic acids otulutsidwa ndi oyera komanso olondola..
