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Methylfolate (L-5 Methyl Calcium Tetrahydrofolate) CAS:134-35-0 Wopanga Wogulitsa
5-Methyltetrahydrofolic acid (5-MTHF) ndi metabolite yogwira ntchito ya folate. Imagwira ntchito yofunika kwambiri pakupanga methionine kuchokera ku homocysteine popereka gulu la methyl. 5-Methyltetrahydrofolic acid- (glutamic acid-13C5) ndi isotope ya vitamini B9 pomwe ma glutamate carbon onse asanu amalowedwa m'malo ndi 13C6 carbon.
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Creatine phosphate CAS: 67-07-2 Wopanga Wogulitsa
Creatine phosphateNdi phosphoamino acid yopangidwa ndi creatine yokhala ndi gulu la phospho lomwe limalumikizidwa ndi nayitrogeni yoyamba ya gulu la guanidino. Ili ndi gawo ngati metabolite ya anthu komanso metabolite ya mbewa. Ndi phosphoamino acid ndi phosphagen. Imagwira ntchito mogwirizana ndi creatine. Ndi conjugate acid ya N-phosphocreatinate (2-).
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Vitamini A Acid CAS: 302-79-4 Wopanga Wogulitsa
Asidi ya retinoic(a)Tretinoin）imagwiritsidwa ntchito kwambiri mu mankhwala a khungu, omwe ndi gawo la vitamini A (Victoria methanol) metabolic intermediates. Imakhudza kwambiri kukula kwa mafupa ndi kagayidwe ka epithelial, imatha kulimbikitsa kuchulukana kwa maselo a epithelial ndikusintha, komanso imatha kuletsa kuchulukana ndi kusiyanitsa kwa keratinocytes, kotero hyperkeratosis ikhoza kubwerera mwakale. Chifukwa chake, matenda ambiri a hyperkeratosis athunthu kapena osakwanira amakhala ndi zotsatira zina zochiritsira, kuchiza matenda osiyanasiyana akhungu. Kugwiritsa ntchito mankhwalawa kumatha kulowa pakhungu mwachangu, kupangitsa kuti maselo a epithelial achuluke kwambiri. Gulu la mankhwalawa lili ndi kuletsa kwamphamvu komanso mwachangu kutulutsa kwa sebaceous glands, kumatha kuchepetsa kutulutsa kwa sebum. Kuphatikiza apo, mankhwalawa alinso ndi anti-chotupa, amalimbikitsa machiritso a mabala komanso zotsatira zotsutsana ndi kutupa.
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L-Carnitine CAS: 541-15-1 Wopanga Wogulitsa
L-Carnitine, yomwe imadziwikanso kuti L-carnitine ndi vitamini BT, fomula ya mankhwala ndi C7H15NO3, dzina la mankhwala ndi (R)-3-carboxyl-2-hydroxy-n, N, n-trimethylammonium propionate hydroxide internal salt, ndipo mankhwala oimira ndi L-carnitine. Ndi mtundu wa amino acid womwe umalimbikitsa kusintha kwa mafuta kukhala mphamvu.
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Chromium Polynicotinate CAS: 64452-96-6 Wopanga Wogulitsa
Chromium Polynicotinate ndi ufa wosalala wa imvi yosuta. Mankhwalawa ndi okhazikika kutentha kwa chipinda ndipo sasungunuka m'madzi ndi ethanol. Mphamvu ya chromium ndi 3+. Amagwiritsidwa ntchito makamaka mu zowonjezera zakudya, zinthu zachipatala, zowonjezera zakudya, ndi zina zotero. Ntchito yake ndikulimbikitsa kukula ndi chitukuko cha nyama, kufulumizitsa kupanga, komanso kulimbikitsa kupanga mapuloteni.
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N-Acetyl-D-Glucosamine CAS: 7512-17-6 Wopanga Wogulitsa
N-Acetyl-D-Glucosamine ndi chinthu chochokera ku N-acetyl chomwe chimachokera ku glucosamine. Mwa mankhwala, ndi amide pakati pa glucosamine ndi acetic acid. Gawo limodzi la N-acetylglucosamine lomwe limalumikizidwa ndi zotsalira za serine kapena threonine pa mapuloteni a nyukiliya ndi cytoplasmic -O-GlcNAc, ndi kusintha kwa mapuloteni komwe kumachitika pambuyo pa kusinthika. Mapuloteni osinthidwa a O-GlcNAc amakhudzidwa pozindikira momwe michere ilili m'malo ozungulira maselo ndikusintha momwe mapuloteni amagwirira ntchito moyenera. O-GlcNAc imayang'anira mayankho a maselo ku mahomoni monga insulin, imayambitsa yankho loteteza ku kupsinjika, imasintha mphamvu ya selo kukula ndikugawa, ndikulamulira kulembedwa kwa majini. Mwa anthu, imapezeka pakhungu, cartilage ndi mtsempha wamagazi ngati gawo la hyaluronic acid, ndi minofu ya mafupa, cornea ndi aorta ngati gawo la keratan sulfate.
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Creatine Pyruvate CAS: 55965-97-4 Wopanga Wopanga
Creatine Pyruvate ndi mankhwala omwe ali ndi Creatine ndi pyruvic acid ndipo amagwiritsidwa ntchito ndi opanga thupi ngati chowonjezera kuti apeze zotsatira zoyambitsa matenda ndipo amasungunuka kwathunthu m'madzi. Mu mawonekedwe ake ophatikizika, Creatine Pyruvate imasungunuka nthawi 10 kuposa momwe imakhalira payokha. Kafukufuku wazachipatala wasonyeza kuti Pyruvate imachepetsa mafuta m'thupi popanda kukhudza mapuloteni a minofu, chinthu chofunikira kwambiri pakukwaniritsa minofu yowonda. Zowonjezera za Creatine Pyruvate ndi chithandizo chabwino kwambiri cha zakudya kwa othamanga omwe akufuna kukulitsa mphamvu ya minofu ndi kupirira pamapulogalamu olimbitsa thupi amphamvu.
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Vitamini A Palmitat CAS: 79-81-2 Wopanga Wogulitsa
Retinyl palmitate ndi m'gulu la mankhwala otchedwa retinoids, omwe ali ngati vitamini A m'mankhwala. Amathandiza kwambiri pa masomphenya, khungu ndi chitetezo chamthupi, amaletsa kuchulukana kwa maselo komanso amaletsa khansa. Ndi chakudya chofunikira komanso mankhwala ochiritsira. All-trans-retinyl palmitate ndi all-trans-retinyl ester yomwe imapezeka mwa kusungunuka kwa gulu la carboxy la palmitic (hexadecanoic acid) ndi gulu la hydroxy la all-trans-retinol. Amagwiritsidwa ntchito mu zodzoladzola pochiza matenda osiyanasiyana a pakhungu monga ziphuphu, ukalamba wa khungu, makwinya, mawanga akuda, komanso kuteteza ku psoriasis. Ili ndi gawo ngati metabolite ya Escherichia coli, metabolite ya xenobiotic ya anthu komanso antioxidant. Ndi retinyl palmitate ndi all-trans-retinyl ester. Imagwira ntchito mogwirizana ndi all-trans-retinol.
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Benfotiamine CAS:22457-89-2 Wopanga Wogulitsa
S-Benzoylthiamine O-monophosphate (Benfotiamine) ndi chinthu chochokera ku S-acyl thiamine chomwe chimachokera ku amphiphilic. Ndi vitamini wosungunuka ndi mafuta. Benfotiamine ili ndi mphete ya thiazole. Benfotiamine imapezeka kwambiri kuposa thiamine.
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Kolajeni Hydrolyzed CAS: 92113-31-0 Wopanga Wogulitsa
Kolajeni ya hydrolyzed imatchedwanso hydrolyzed collagen. Kolajeni ya hydrolyzed ndi mtundu watsopano wa chinthu cha collagen, chomwe chimapangidwa kuchokera ku collagen kapena zinthu zambiri za collagen. Kuwonjezera pa kapangidwe ka amino acid ka collagen (pafupifupi 30% ya zotsalira zonse za amino acid ndi glycine), ilinso ndi 15-30% ya ma amino acid awiri omwe sapezeka kawirikawiri m'mapuloteni ena, proline ndi 4-hydroxyproline Kuwonjezera pa asidi), ilinso ndi makhalidwe a kulemera kochepa kwa mamolekyulu, ndipo kapangidwe kake kamakhala ndi ma peptide ang'onoang'ono okhala ndi kulemera kwa mamolekyulu osakwana 3000.
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Vitamini E Yachilengedwe CAS: 59-02-9 Wopanga Wogulitsa
Mafuta a Vitamini E ndi vitamini wosungunuka ndi mafuta, wotchedwanso tocopherol. Ndi imodzi mwa ma antioxidants ofunikira kwambiri. Ndi zinthu zosungunulira mafuta monga ethanol, ndipo sizisungunuka m'madzi, kutentha, asidi wokhazikika, base-labile. Ndi womasuka ndi mpweya koma samasuka ndi kutentha. Ndipo ntchito ya vitamini E inali yotsika kwambiri pakukazinga. α-Tocopherol imapangidwa kuchokera ku γ-tocopherol pogwiritsa ntchito enzyme γ-tocopherol methyltransferase. Ndi mtundu waukulu wa Vitamini E m'magazi a anthu. Imapezeka mu mafuta a mbewu ya mpendadzuwa.
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Curcumin (turmeric) 95% CAS:458-37-7 Wogulitsa Wopanga
Curcumin ndiye mtundu waukulu wachikasu mu turmeric ndi curry ndipo uli ndi ntchito zotsutsana ndi antioxidant, anti-inflammatory, komanso antitumor. Imaletsa kupanga nitric oxide (NO) (IC50 = 6 μM) ndipo imachepetsa ntchito ya nitric oxide synthase (iNOS) mu maselo a RAW 264.7 omwe amalimbikitsidwa ndi LPS. Curcumin imaletsa kutulutsidwa kwa histamine ndi ma cytokines otupa a TNF-α, IL-1β, IL-6, ndi IL-8 kuchokera ku maselo a HMC-1 mast. Mu thupi, curcumin imachepetsa kuchuluka kwa histamine ndi TNF-α mu seramu, imaletsa kusintha kwa histopathological kwa mucosa wa m'mphuno, komanso imachepetsa kuchuluka kwa kuyetsemula ndi kukanda m'mphuno mu chitsanzo cha mbewa cha ovalbumin-induced rhinitis.
